Stadium: Cameron Indoor Stadium
Home Manager: Mike Krzyzewski Away Manager: Dustin Kerns
| NCAAB | 2021/12/13 08:27 | Appalachian State v Erskine | W | 69-44 |
| NCAAB | 2021/12/11 00:00 | Appalachian State v Furman | L | 65-73 |
| NCAAB | 2021/12/02 00:30 | Appalachian State v Boyce | W | 90-29 |
| NCAAB | 2021/11/29 23:30 | Hartford v Appalachian State | W | 59-69 |
| NCAAB | 2021/11/24 18:30 | Vermont v Appalachian State | L | 65-63 |
| NCAAB | 2021/11/23 18:30 | Akron v Appalachian State | W | 45-57 |
| NCAAB | 2021/11/23 00:30 | Appalachian State v Delaware | L | 68-75 |
| NCAAB | 2021/11/18 23:30 | Charlotte U v Appalachian State | L | 67-66 |
| NCAAB | 2021/12/15 01:00 | South Carolina State v Duke | W | 62-103 |
| NCAAB | 2021/12/01 02:30 | Duke v Ohio State | L | 66-71 |
| NCAAB | 2021/11/27 03:30 | Duke v Gonzaga | W | 84-81 |
| NCAAB | 2021/11/23 02:00 | The Citadel v Duke | W | 81-107 |
| NCAAB | 2021/11/20 01:00 | Lafayette v Duke | W | 55-88 |
| NCAAB | 2021/11/17 00:00 | Gardner Webb v Duke | W | 52-92 |
| NCAAB | 2021/11/14 01:00 | Campbell v Duke | W | 56-67 |
| NCAAB | 2021/11/13 00:00 | Army v Duke | W | 56-82 |