Stadium: Littlejohn Coliseum
Home Manager: Brad Brownell Away Manager: Steve Forbes
| NCAAB | 2021/02/24 21:30 | Clemson v Wake Forest | L | 60-39 |
| NCAAB | 2020/02/02 01:00 | Clemson v Wake Forest | W | 44-56 |
| NCAAB | 2020/01/22 01:00 | Wake Forest v Clemson | L | 68-71 |
| NCAAB | 2019/02/03 17:00 | Wake Forest v Clemson | L | 37-64 |
| NCAAB | 2018/02/03 19:00 | Clemson v Wake Forest | L | 75-67 |
| NCAAB | 2017/02/15 00:00 | Wake Forest v Clemson | L | 83-95 |
| NCAAB | 2016/12/31 17:00 | Clemson v Wake Forest | L | 73-68 |
| NCAAB | 2016/02/03 01:00 | Wake Forest v Clemson | L | 62-76 |
| NCAAB | 2022/02/19 18:00 | Notre Dame v Wake Forest | W | 74-79 |
| NCAAB | 2022/02/16 00:00 | Wake Forest v Duke | L | 74-76 |
| NCAAB | 2022/02/12 20:00 | Miami Florida v Wake Forest | L | 76-72 |
| NCAAB | 2022/02/10 00:00 | Wake Forest v NC State | W | 69-51 |
| NCAAB | 2022/02/05 17:00 | Wake Forest v Florida State | W | 68-60 |
| NCAAB | 2022/02/03 00:00 | Pittsburgh v Wake Forest | W | 75-91 |
| NCAAB | 2022/01/30 01:00 | Wake Forest v Syracuse | L | 72-94 |
| NCAAB | 2022/01/24 23:00 | Boston College v Wake Forest | W | 57-87 |
| NCAAB | 2022/02/19 20:00 | Clemson v Louisville | L | 61-70 |
| NCAAB | 2022/02/16 00:00 | Clemson v Florida State | L | 80-81 |
| NCAAB | 2022/02/13 00:00 | Notre Dame v Clemson | L | 76-61 |
| NCAAB | 2022/02/11 01:00 | Duke v Clemson | L | 82-64 |
| NCAAB | 2022/02/08 23:00 | North Carolina v Clemson | L | 79-77 |
| NCAAB | 2022/02/05 19:00 | Clemson v Georgia Tech | L | 64-69 |
| NCAAB | 2022/02/03 00:00 | Florida State v Clemson | W | 69-75 |
| NCAAB | 2022/01/26 00:00 | Clemson v Duke | L | 69-71 |