Stadium: William D. Mullins Center
Home Manager: Matt McCall Away Manager: Micah Shrewsberry
| NCAAB | 2021/11/11 01:30 | Youngstown State v Penn State | W | 59-75 |
| NCAAB | 2021/03/12 01:55 | Penn State v Wisconsin | L | 74-75 |
| NCAAB | 2021/03/11 02:00 | Nebraska v Penn State | W | 66-72 |
| NCAAB | 2021/03/08 00:00 | Penn State v Maryland | W | 66-61 |
| NCAAB | 2021/03/04 00:00 | Minnesota v Penn State | W | 65-84 |
| NCAAB | 2021/02/27 00:00 | Purdue v Penn State | L | 73-52 |
| NCAAB | 2021/02/24 01:00 | Penn State v Nebraska | W | 86-83 |
| NCAAB | 2021/02/21 22:00 | Penn State v Iowa | L | 68-74 |
| NCAAB | 2021/11/13 01:00 | Massachusetts v Yale | L | 71-91 |
| NCAAB | 2021/11/10 00:30 | UMBC v Massachusetts | W | 60-77 |
| NCAAB | 2021/03/05 18:00 | Massachusetts v St Louis | L | 72-86 |
| NCAAB | 2021/03/04 18:00 | St Josephs v Massachusetts | W | 66-100 |
| NCAAB | 2021/03/01 23:00 | Massachusetts v St Louis | L | 57-78 |
| NCAAB | 2021/02/23 23:00 | Massachusetts v Richmond | L | 65-79 |
| NCAAB | 2021/02/07 01:00 | Massachusetts v Rhode Island | W | 75-63 |
| NCAAB | 2021/02/03 23:00 | Fordham v Massachusetts | W | 54-60 |