Stadium: Willett Hall
Home Manager: Mike Brennan Away Manager: Justin Gray
| NCAAB | 2021/11/20 00:30 | Western Carolina v UMBC | L | 75-91 |
| NCAAB | 2021/11/14 21:00 | Western Carolina v East Carolina | L | 79-95 |
| NCAAB | 2021/11/13 00:30 | Western Carolina v Wake Forest | L | 75-87 |
| NCAAB | 2021/11/10 00:30 | Bowling Green v Western Carolina | W | 71-79 |
| NCAAB | 2021/03/05 22:30 | Western Carolina v The Citadel | L | 86-100 |
| NCAAB | 2021/02/27 18:00 | Mercer v Western Carolina | W | 61-85 |
| NCAAB | 2021/02/25 00:00 | Western Carolina v NC Greensboro | W | 81-80 |
| NCAAB | 2021/02/22 22:00 | NC Greensboro v Western Carolina | L | 77-56 |
| NCAAB | 2021/11/19 22:00 | American v Longwood | L | 42-82 |
| NCAAB | 2021/11/17 01:30 | American v Georgetown | L | 57-79 |
| NCAAB | 2021/11/13 00:00 | American v William & Mary | W | 74-62 |
| NCAAB | 2021/11/10 01:00 | Marist v American | W | 73-77 |
| NCAAB | 2021/03/06 20:00 | American v Army | L | 66-89 |
| NCAAB | 2021/02/28 21:00 | Bucknell v American | W | 68-81 |
| NCAAB | 2021/02/27 19:00 | American v Bucknell | W | 78-71 |
| NCAAB | 2021/02/25 00:00 | American v Loyola Maryland | L | 49-60 |