Stadium: Michael J. Hagan '85 Arena
Home Manager: Billy Lange Away Manager: Levell Sanders
| NCAAB | 2021/11/28 19:00 | Binghamton v Hartwick Hawks | W | 110-41 |
| NCAAB | 2021/11/20 17:00 | Binghamton v Connecticut | L | 63-87 |
| NCAAB | 2021/11/18 00:00 | Binghamton v Columbia | L | 77-85 |
| NCAAB | 2021/11/14 18:00 | Binghamton v Sacred Heart | W | 72-60 |
| NCAAB | 2021/11/10 00:30 | Cornell v Binghamton | L | 76-69 |
| NCAAB | 2021/02/27 19:00 | Binghamton v Hartford | L | 60-77 |
| NCAAB | 2021/02/21 20:00 | Binghamton v NJIT | W | 72-58 |
| NCAAB | 2021/02/20 21:00 | Binghamton v NJIT | W | 76-63 |
| NCAAB | 2021/11/27 02:00 | St Josephs v Georgetown | W | 77-74 |
| NCAAB | 2021/11/26 02:30 | USC Trojans v St Josephs | L | 70-55 |
| NCAAB | 2021/11/20 17:00 | Monmouth v St Josephs | L | 87-75 |
| NCAAB | 2021/11/18 00:00 | Drexel v St Josephs | L | 78-75 |
| NCAAB | 2021/11/13 18:00 | Mount St Marys v St Josephs | W | 60-80 |
| NCAAB | 2021/11/10 01:00 | Maryland Eastern-Shore v St Josephs | W | 67-69 |
| NCAAB | 2021/03/04 18:00 | St Josephs v Massachusetts | L | 66-100 |
| NCAAB | 2021/03/03 16:00 | St Josephs v La Salle | W | 72-66 |