Stadium: Welsh-Ryan Arena
Home Manager: Chris Collins Away Manager: Tubby Smith
| NCAAB | 2021/11/10 01:00 | High Point v Shenandoah University | W | 108-59 |
| NCAAB | 2021/03/01 23:00 | High Point v Winthrop | L | 54-83 |
| NCAAB | 2021/02/27 21:00 | USC Upstate v High Point | W | 60-65 |
| NCAAB | 2021/02/24 00:00 | High Point v Campbell | L | 48-68 |
| NCAAB | 2021/02/20 00:00 | Winthrop v High Point | L | 71-63 |
| NCAAB | 2021/02/19 02:00 | Winthrop v High Point | L | 76-70 |
| NCAAB | 2021/02/12 23:00 | Charleston Southern v High Point | L | 69-68 |
| NCAAB | 2021/02/11 23:00 | Charleston Southern v High Point | W | 73-77 |
| NCAAB | 2021/11/10 01:00 | Eastern Illinois v Northwestern | W | 56-80 |
| NCAAB | 2021/03/10 23:30 | Minnesota v Northwestern | L | 51-46 |
| NCAAB | 2021/03/07 18:30 | Nebraska v Northwestern | W | 78-79 |
| NCAAB | 2021/03/04 02:00 | Maryland v Northwestern | W | 55-60 |
| NCAAB | 2021/02/26 02:00 | Northwestern v Minnesota | W | 67-59 |
| NCAAB | 2021/02/22 00:00 | Wisconsin v Northwestern | L | 68-51 |
| NCAAB | 2021/02/17 02:00 | Northwestern v Illinois | L | 66-73 |
| NCAAB | 2021/02/13 22:00 | Northwestern v Rutgers | L | 50-64 |