Stadium: Wintrust Arena
Home Manager: Tony Stubblefield Away Manager: Robert Jeter IV
| NCAAB | 2021/11/17 00:00 | Western Illinois v Iowa Wesleyan | W | 97-71 |
| NCAAB | 2021/11/13 00:00 | Western Illinois v Culver-Stockton Wildcats | W | 91-69 |
| NCAAB | 2021/11/10 01:00 | Western Illinois v Nebraska | W | 75-74 |
| NCAAB | 2021/03/07 02:45 | Western Illinois v South Dakota | L | 69-86 |
| NCAAB | 2021/02/28 22:00 | Western Illinois v Oral Roberts | L | 59-95 |
| NCAAB | 2021/02/27 22:00 | Western Illinois v Oral Roberts | L | 81-85 |
| NCAAB | 2021/02/14 01:00 | Denver v Western Illinois | W | 75-82 |
| NCAAB | 2021/02/13 01:00 | Denver v Western Illinois | W | 69-75 |
| NCAAB | 2021/11/19 01:30 | Rutgers v DePaul | W | 70-73 |
| NCAAB | 2021/11/13 23:00 | Central Michigan v DePaul | W | 66-99 |
| NCAAB | 2021/11/11 02:00 | Coppin State v DePaul | W | 72-97 |
| NCAAB | 2021/03/12 02:00 | DePaul v Connecticut | L | 60-94 |
| NCAAB | 2021/03/11 02:00 | DePaul v Providence | W | 70-62 |
| NCAAB | 2021/03/03 02:00 | Marquette v DePaul | L | 77-71 |
| NCAAB | 2021/02/27 17:00 | Georgetown v DePaul | L | 68-60 |
| NCAAB | 2021/02/25 02:00 | DePaul v Creighton | L | 53-77 |