Stadium: Redbird Arena
Home Manager: Dan Muller Away Manager: Wayne Brent
| NCAAB | 2021/12/01 02:00 | Jackson State v Marquette | L | 54-83 |
| NCAAB | 2021/11/27 17:00 | Jackson State v UL Lafayette | W | 75-70 |
| NCAAB | 2021/11/24 00:00 | Jackson State v Indiana | L | 35-70 |
| NCAAB | 2021/11/21 21:00 | Jackson State v Marshall | L | 66-80 |
| NCAAB | 2021/11/17 03:00 | Jackson State v California Baptist | L | 64-77 |
| NCAAB | 2021/11/13 00:30 | Jackson State v Louisiana Tech | L | 68-70 |
| NCAAB | 2021/11/10 01:00 | Jackson State v Illinois | L | 47-71 |
| NCAAB | 2021/03/12 20:00 | Texas Southern v Jackson State | L | 84-81 |
| NCAAB | 2021/12/02 01:00 | Missouri State v Illinois St | W | 74-79 |
| NCAAB | 2021/11/28 02:00 | Illinois St v Purdue Northwest | W | 81-71 |
| NCAAB | 2021/11/24 23:00 | Buffalo v Illinois St | L | 106-90 |
| NCAAB | 2021/11/24 01:30 | Illinois St v St Louis | L | 76-82 |
| NCAAB | 2021/11/21 00:00 | Bucknell v Illinois St | W | 100-105 |
| NCAAB | 2021/11/17 01:00 | Murray State v Illinois St | L | 77-65 |
| NCAAB | 2021/11/12 23:00 | Illinois St v Eastern Michigan | L | 98-103 |
| NCAAB | 2021/11/10 01:00 | UNC Wilmington v Illinois St | W | 63-68 |