Stadium: Fertitta Center
Home Manager: Kelvin Sampson Away Manager: Mike McConathy
| NCAAB | 2021/11/28 21:00 | Stephen F Austin v Northwestern State | L | 72-68 |
| NCAAB | 2021/11/22 20:00 | Northwestern State v UL Monroe | L | 66-96 |
| NCAAB | 2021/11/20 01:30 | Louisiana Tech v Northwestern State | L | 83-64 |
| NCAAB | 2021/11/16 01:00 | Northwestern State v SMU | L | 48-95 |
| NCAAB | 2021/11/14 01:30 | Northwestern State v Champion Christian | W | 91-62 |
| NCAAB | 2021/11/11 01:00 | Northwestern State v Tulsa | L | 75-82 |
| NCAAB | 2021/11/10 01:00 | Northwestern State v Oklahoma | L | 59-77 |
| NCAAB | 2021/03/12 23:00 | Northwestern State v Nicholls State | L | 76-88 |
| NCAAB | 2021/11/24 19:30 | Houston v Oregon | W | 78-49 |
| NCAAB | 2021/11/23 22:00 | Wisconsin v Houston | L | 65-63 |
| NCAAB | 2021/11/22 21:30 | Butler v Houston | W | 52-70 |
| NCAAB | 2021/11/17 01:00 | Virginia v Houston | W | 47-67 |
| NCAAB | 2021/11/13 01:00 | Rice v Houston | W | 46-79 |
| NCAAB | 2021/11/10 01:00 | Hofstra v Houston | W | 75-83 |
| NCAAB | 2021/04/03 21:14 | Houston v Baylor Bears | L | 59-78 |
| NCAAB | 2021/03/29 23:15 | Oregon State v Houston | W | 61-67 |