Stadium: Sam M. Vadalabene Center
Home Manager: Brian Barone Away Manager: Brian Collins
| NCAAB | 2021/02/04 19:00 | Tennessee State v SIU Edwardsville | L | 60-68 |
| NCAAB | 2021/01/22 02:00 | SIU Edwardsville v Tennessee State | L | 67-65 |
| NCAAB | 2020/01/04 22:00 | SIU Edwardsville v Tennessee State | W | 74-79 |
| NCAAB | 2019/02/22 01:30 | SIU Edwardsville v Tennessee State | L | 85-84 |
| NCAAB | 2018/01/26 01:30 | SIU Edwardsville v Tennessee State | W | 57-85 |
| NCAAB | 2018/01/14 01:00 | Tennessee State v SIU Edwardsville | L | 79-82 |
| NCAAB | 2017/01/26 01:00 | Tennessee State v SIU Edwardsville | W | 76-56 |
| NCAAB | 2016/01/10 01:30 | Tennessee State v SIU Edwardsville | W | 63-60 |
| NCAAB | 2022/01/25 00:00 | Tennessee State v Morehead State | L | 54-67 |
| NCAAB | 2022/01/22 21:00 | Austin Peay v Tennessee State | W | 61-65 |
| NCAAB | 2022/01/21 01:00 | Tennessee State v SE Missouri State | L | 63-85 |
| NCAAB | 2022/01/17 19:00 | Tennessee Tech v Tennessee State | W | 64-80 |
| NCAAB | 2022/01/15 21:00 | Morehead State v Tennessee State | L | 71-64 |
| NCAAB | 2022/01/14 01:00 | Tennessee State v Murray State | L | 44-67 |
| NCAAB | 2022/01/08 21:00 | SE Missouri State v Tennessee State | W | 84-95 |
| NCAAB | 2022/01/07 00:00 | Tennessee Martin v Tennessee State | L | 94-78 |
| NCAAB | 2022/01/25 01:00 | SIU Edwardsville v Tennessee Martin | L | 70-76 |
| NCAAB | 2022/01/22 21:00 | SIU Edwardsville v Morehead State | L | 74-77 |
| NCAAB | 2022/01/21 00:00 | SIU Edwardsville v Tennessee Tech | L | 76-94 |
| NCAAB | 2022/01/18 00:00 | Belmont v SIU Edwardsville | L | 80-64 |
| NCAAB | 2022/01/14 02:00 | SIU Edwardsville v Eastern Illinois | W | 66-53 |
| NCAAB | 2022/01/08 21:00 | Murray State v SIU Edwardsville | L | 74-69 |
| NCAAB | 2021/12/22 01:00 | SIU Edwardsville v South Alabama | L | 69-84 |
| NCAAB | 2021/12/19 19:00 | William Woods v SIU Edwardsville | W | 29-84 |