Stadium: The Buc Dome
Home Manager: Barclay Radebaugh Away Manager: Mark Prosser
| NCAAB | 2021/01/05 20:00 | Winthrop v Charleston Southern | W | 78-76 |
| NCAAB | 2021/01/04 21:00 | Winthrop v Charleston Southern | W | 85-69 |
| NCAAB | 2020/01/31 00:30 | Winthrop v Charleston Southern | W | 77-60 |
| NCAAB | 2019/03/07 19:00 | Charleston Southern v Winthrop | L | 77-63 |
| NCAAB | 2019/02/23 19:00 | Charleston Southern v Winthrop | W | 78-80 |
| NCAAB | 2019/02/08 00:30 | Winthrop v Charleston Southern | W | 76-72 |
| NCAAB | 2018/02/24 19:00 | Charleston Southern v Winthrop | L | 78-75 |
| NCAAB | 2018/01/13 00:30 | Charleston Southern v Winthrop | W | 53-64 |
| NCAAB | 2022/01/14 00:00 | UNC Asheville v Winthrop | W | 80-86 |
| NCAAB | 2022/01/10 22:00 | Campbell v Winthrop | W | 72-74 |
| NCAAB | 2021/12/31 18:00 | Winthrop v Converse Valkyries | W | 78-40 |
| NCAAB | 2021/12/22 00:00 | Winthrop v Mississippi State | L | 63-84 |
| NCAAB | 2021/12/16 00:00 | Winthrop v Elon | L | 61-63 |
| NCAAB | 2021/12/12 00:00 | Winthrop v Carver | W | 83-52 |
| NCAAB | 2021/12/08 00:00 | Furman v Winthrop | W | 80-85 |
| NCAAB | 2021/12/04 18:00 | Winthrop v Coastal Carolina | L | 64-74 |
| NCAAB | 2022/01/13 00:00 | Charleston Southern v Campbell | L | 52-67 |
| NCAAB | 2022/01/08 21:30 | Charleston Southern v UNC Asheville | L | 59-82 |
| NCAAB | 2022/01/06 00:00 | Gardner Webb v Charleston Southern | L | 88-63 |
| NCAAB | 2021/12/21 22:00 | South Carolina State v Charleston Southern | L | 75-65 |
| NCAAB | 2021/12/21 00:00 | Manhattan v Charleston Southern | L | 99-75 |
| NCAAB | 2021/12/17 01:00 | Tennessee State v Charleston Southern | L | 78-75 |
| NCAAB | 2021/12/06 01:00 | Charleston Southern v Tarleton State | W | 59-57 |
| NCAAB | 2021/12/03 01:00 | Jacksonville v Charleston Southern | L | 67-56 |