Stadium: Pete Hanna Center
Home Manager: Bucky McMillan Away Manager: Randy Bolden
| NCAAB | 2021/11/27 18:30 | McNeese State v Samford | W | 75-83 |
| NCAAB | 2021/11/26 16:00 | Samford v North Carolina A&T | W | 77-75 |
| NCAAB | 2021/11/19 02:00 | Samford v Oregon State | W | 78-77 |
| NCAAB | 2021/11/16 02:00 | Samford v San Francisco | L | 55-77 |
| NCAAB | 2021/11/12 00:00 | Samford v Spring Hill | W | 86-69 |
| NCAAB | 2021/11/10 00:00 | Samford v Maryville Scots | W | 99-78 |
| NCAAB | 2021/03/06 01:00 | Samford v Mercer | L | 59-87 |
| NCAAB | 2021/02/18 00:00 | Samford v Furman | L | 64-78 |
| NCAAB | 2021/01/30 20:30 | Mississippi College v Christian Brothers | W | 72-60 |
| NCAAB | 2021/01/30 00:30 | Mississippi College v Christian Brothers | L | 62-67 |
| NCAAB | 2021/01/23 20:30 | Mississippi College v Union University Bulldogs (Tn) | W | 89-57 |
| NCAAB | 2021/01/23 00:30 | Mississippi College v Union University Bulldogs (Tn) | L | 61-75 |
| NCAAB | 2021/01/13 23:00 | West Alabama v Mississippi College | L | 67-49 |
| NCAAB | 2021/01/13 00:00 | West Alabama v Mississippi College | L | 70-64 |
| NCAAB | 2021/01/03 20:00 | Alabama-Huntsville v Mississippi College | L | 91-79 |
| NCAAB | 2021/01/02 22:00 | Alabama-Huntsville v Mississippi College | L | 73-72 |