Stadium: Rupp Arena
Home Manager: John Calipari Away Manager: Matthew Driscoll
| NCAAB | 2021/11/20 19:00 | North Florida v Webber International | W | 103-43 |
| NCAAB | 2021/11/18 03:30 | North Florida v UCLA | L | 63-98 |
| NCAAB | 2021/11/16 02:00 | North Florida v Arizona State | L | 63-72 |
| NCAAB | 2021/11/13 02:00 | North Florida v Grand Canyon | L | 51-65 |
| NCAAB | 2021/11/11 01:00 | North Florida v Texas A&M | L | 46-64 |
| NCAAB | 2021/11/10 01:00 | North Florida v Texas Tech | L | 74-89 |
| NCAAB | 2021/03/04 19:47 | North Alabama v North Florida | L | 68-60 |
| NCAAB | 2021/02/27 19:00 | North Florida v Stetson | L | 68-85 |
| NCAAB | 2021/11/23 00:00 | Albany NY v Kentucky | W | 61-86 |
| NCAAB | 2021/11/20 00:00 | Ohio v Kentucky | W | 59-77 |
| NCAAB | 2021/11/17 00:00 | Mount St Marys v Kentucky | W | 55-80 |
| NCAAB | 2021/11/13 00:00 | Robert Morris v Kentucky | W | 60-100 |
| NCAAB | 2021/11/10 02:30 | Kentucky v Duke | L | 71-79 |
| NCAAB | 2021/03/11 17:00 | Mississippi State v Kentucky | L | 74-73 |
| NCAAB | 2021/03/06 17:00 | SC Gamecocks v Kentucky | W | 64-92 |
| NCAAB | 2021/03/03 02:00 | Kentucky v Mississippi | L | 62-70 |