Stadium: Daskalakis Athletic Center
Home Manager: Zach Spiker Away Manager: Dane Fischer
| NCAAB | 2021/01/23 18:00 | Drexel v William & Mary | L | 79-64 |
| NCAAB | 2021/01/17 18:00 | William & Mary v Drexel | W | 69-64 |
| NCAAB | 2021/01/16 18:00 | William & Mary v Drexel | L | 58-82 |
| NCAAB | 2020/02/14 00:00 | Drexel v William & Mary | W | 72-77 |
| NCAAB | 2020/01/18 19:00 | William & Mary v Drexel | L | 57-84 |
| NCAAB | 2019/02/01 00:00 | Drexel v William & Mary | W | 69-75 |
| NCAAB | 2019/01/05 21:00 | William & Mary v Drexel | W | 84-66 |
| NCAAB | 2018/02/03 21:00 | Drexel v William & Mary | L | 91-79 |
| NCAAB | 2022/01/21 00:00 | William & Mary v Delaware | L | 74-84 |
| NCAAB | 2022/01/18 00:00 | Towson v William & Mary | L | 91-69 |
| NCAAB | 2022/01/15 21:00 | James Madison v William & Mary | L | 95-91 |
| NCAAB | 2021/12/31 19:00 | Northeastern v William & Mary | W | 70-71 |
| NCAAB | 2021/12/30 00:00 | Hofstra v William & Mary | W | 62-63 |
| NCAAB | 2021/12/22 18:00 | William & Mary v Valparaiso | L | 66-88 |
| NCAAB | 2021/12/12 18:00 | Fairfield v William & Mary | L | 70-47 |
| NCAAB | 2021/12/10 00:00 | Hampton v William & Mary | L | 54-53 |
| NCAAB | 2022/01/21 00:00 | Elon v Drexel | W | 49-77 |
| NCAAB | 2022/01/17 21:00 | Drexel v Hofstra | L | 68-71 |
| NCAAB | 2022/01/15 19:00 | Drexel v Northeastern | W | 76-68 |
| NCAAB | 2022/01/12 00:00 | Delaware v Drexel | L | 81-77 |
| NCAAB | 2022/01/03 23:00 | Towson v Drexel | W | 61-65 |
| NCAAB | 2021/12/15 01:00 | Coppin State v Drexel | W | 69-76 |
| NCAAB | 2021/12/12 00:00 | Drexel v Abilene Christian | L | 56-73 |
| NCAAB | 2021/12/04 21:00 | Drexel v Princeton | L | 79-81 |