[1] UC Irvine 69-64 Santa Clara [19] 2021-11-28 00:30
Stadium: Leavey Center
Home Manager: Herb Sendek Away Manager: Russell Turner
Head to Head
| NCAAB | 2018/11/16 03:00 | UC Irvine v Santa Clara | W | 61-49 |
| NCAAB | 2016/12/01 03:00 | Santa Clara v UC Irvine | W | 55-58 |
| NCAAB | 2015/11/24 03:00 | UC Irvine v Santa Clara | W | 79-61 |
| NCAAB | 2005/11/22 12:00 | UC Irvine v Santa Clara | W | 78-70 |
| NCAAB | 2004/12/14 12:00 | Santa Clara v UC Irvine | W | 58-70 |
Home History
| NCAAB | 2021/11/21 02:00 | Pepperdine v UC Irvine | W | 48-82 |
| NCAAB | 2021/11/17 03:00 | UC Irvine v La Verne | W | 100-41 |
| NCAAB | 2021/11/14 02:00 | Boise State v UC Irvine | W | 50-58 |
| NCAAB | 2021/11/10 02:00 | UC Irvine v New Mexico State | L | 51-62 |
| NCAAB | 2021/03/14 04:30 | UC Irvine v UC Santa Barbara | L | 63-79 |
| NCAAB | 2021/03/13 05:00 | Cal Riverside v UC Irvine | W | 61-78 |
| NCAAB | 2021/03/12 01:00 | Cal Poly SLO v UC Irvine | W | 51-58 |
| NCAAB | 2021/03/07 00:00 | UC Irvine v Long Beach State | W | 73-58 |
Away History
| NCAAB | 2021/11/25 06:00 | Fresno St v Santa Clara | L | 59-52 |
| NCAAB | 2021/11/23 03:30 | TCU v Santa Clara | W | 66-85 |
| NCAAB | 2021/11/20 02:00 | Cal Poly SLO v Santa Clara | W | 57-87 |
| NCAAB | 2021/11/17 02:00 | Nevada v Santa Clara | W | 74-96 |
| NCAAB | 2021/11/13 04:00 | Stanford v Santa Clara | W | 72-88 |
| NCAAB | 2021/11/10 02:00 | CS Fullerton v Santa Clara | W | 77-84 |
| NCAAB | 2021/03/07 05:00 | Santa Clara v Pepperdine | L | 70-78 |
| NCAAB | 2021/03/06 05:00 | Santa Clara v Pacific | W | 81-76 |