Stadium: State Farm Center
Home Manager: Brad Underwood Away Manager: Tom Izzo
| NCAAB | 2021/02/24 00:00 | Illinois v Michigan State | W | 72-81 |
| NCAAB | 2020/02/12 02:00 | Michigan State v Illinois | W | 70-69 |
| NCAAB | 2020/01/03 01:00 | Illinois v Michigan State | W | 56-76 |
| NCAAB | 2019/02/06 00:00 | Michigan State v Illinois | L | 74-79 |
| NCAAB | 2018/02/21 00:00 | Illinois v Michigan State | W | 61-81 |
| NCAAB | 2018/01/23 02:00 | Michigan State v Illinois | W | 87-74 |
| NCAAB | 2017/03/02 02:00 | Michigan State v Illinois | L | 70-73 |
| NCAAB | 2016/01/08 02:00 | Michigan State v Illinois | W | 79-54 |
| NCAAB | 2022/01/22 02:00 | Michigan State v Wisconsin | W | 86-74 |
| NCAAB | 2022/01/15 17:00 | Northwestern v Michigan State | L | 64-62 |
| NCAAB | 2022/01/13 00:00 | Minnesota v Michigan State | W | 69-71 |
| NCAAB | 2022/01/06 00:00 | Nebraska v Michigan State | W | 67-79 |
| NCAAB | 2022/01/02 19:00 | Michigan State v Northwestern | W | 73-67 |
| NCAAB | 2021/12/29 20:00 | High Point v Michigan State | W | 68-81 |
| NCAAB | 2021/12/22 00:30 | Michigan State v Oakland | W | 90-78 |
| NCAAB | 2021/12/11 19:00 | Penn State v Michigan State | W | 64-80 |
| NCAAB | 2022/01/22 00:00 | Illinois v Maryland | L | 65-81 |
| NCAAB | 2022/01/17 17:00 | Purdue v Illinois | L | 96-88 |
| NCAAB | 2022/01/15 02:00 | Michigan v Illinois | W | 53-68 |
| NCAAB | 2022/01/12 01:30 | Illinois v Nebraska | W | 81-71 |
| NCAAB | 2022/01/07 00:00 | Maryland v Illinois | W | 64-76 |
| NCAAB | 2022/01/05 00:00 | Illinois v Minnesota | W | 76-53 |
| NCAAB | 2021/12/23 02:00 | Illinois v Missouri | W | 88-63 |
| NCAAB | 2021/12/18 18:00 | St Francis PA v Illinois | W | 48-106 |