Stadium: Joseph G. Echols Memorial Hall
Home Manager: Robert Jones Away Manager: Dane Fischer
| NCAAB | 2021/11/13 00:00 | American v William & Mary | L | 74-62 |
| NCAAB | 2021/11/11 00:00 | William & Mary v Wake Forest | L | 59-77 |
| NCAAB | 2021/03/07 23:00 | William & Mary v Northeastern | L | 47-63 |
| NCAAB | 2021/03/07 00:00 | UNC Wilmington v William & Mary | W | 60-73 |
| NCAAB | 2021/02/23 00:00 | William & Mary v Elon | L | 54-73 |
| NCAAB | 2021/02/20 19:00 | Elon v William & Mary | L | 75-54 |
| NCAAB | 2021/01/31 18:00 | William & Mary v Towson | W | 75-74 |
| NCAAB | 2021/01/30 18:00 | William & Mary v Towson | W | 84-74 |
| NCAAB | 2021/11/13 22:00 | Tennessee State v Norfolk State | W | 59-66 |
| NCAAB | 2021/11/12 00:00 | Norfolk State v Penn St Wilkes Barre | W | 111-55 |
| NCAAB | 2021/11/10 01:00 | Norfolk State v Bridgewater Eagles | W | 79-56 |
| NCAAB | 2021/03/21 01:20 | Norfolk State v Gonzaga | L | 55-98 |
| NCAAB | 2021/03/19 00:40 | Norfolk State v Appalachian State | W | 54-53 |
| NCAAB | 2021/03/13 18:00 | Morgan State v Norfolk State | W | 63-71 |
| NCAAB | 2021/03/12 02:00 | North Carolina Central v Norfolk State | W | 58-87 |
| NCAAB | 2021/02/28 19:00 | Norfolk State v St Mary's | W | 72-51 |