[3] AEK Athens B 2-1 AE Karaiskakis [9] 2021-11-20 13:00
Round: 3
Home Manager: Sokratis Ofrydopoulos Away Manager: Dragan Djukanovic
Home History
| Greece Super League 2 | 2021/11/14 13:00 | Panathinaikos B v AEK Athens B | W | 0-2 |
| Greece Super League 2 | 2021/11/07 13:00 | AEK Athens B v Kalamata | W | 1-0 |
| Europe Friendlies | 2021/09/08 13:25 | AEK Athens B v Diagoras | D | 0-0 |
| Europe Friendlies | 2021/08/26 15:00 | AEK Athens B v Rhodos | L | 0-1 |
Away History
| Greece Super League 2 | 2021/11/13 13:00 | Karaiskakis v Kifisias FC | L | 0-2 |
| Greece Super League 2 | 2021/11/07 13:00 | Episkopi FC v Karaiskakis | W | 0-1 |
| Greece Cup | 2021/09/26 13:00 | Karaiskakis v Xanthi | L | 0-2 |
| Greece Super League 2 | 2021/05/18 12:30 | Karaiskakis v OF Ierapetras | L | 0-3 |
| Greece Super League 2 | 2021/05/15 11:45 | Apollon Larissa v Karaiskakis | D | 2-2 |
| Greece Super League 2 | 2021/05/08 11:45 | Doxa Drama v Karaiskakis | W | 2-4 |
| Greece Super League 2 | 2021/05/04 12:30 | Karaiskakis v Panachaiki | D | 3-3 |
| Greece Super League 2 | 2021/04/27 12:30 | Trikala v Karaiskakis | W | 0-1 |