Head to Head
| Mexico U20 League | 2021/11/18 15:00 | Leon U20 v Santos Laguna U20 | L | 1-0 |
| Mexico U20 League | 2021/08/21 14:00 | Leon U20 v Santos Laguna U20 | D | 1-1 |
| Mexico U20 League | 2021/03/21 17:00 | Santos Laguna U20 v Leon U20 | W | 3-0 |
| Mexico U20 League | 2020/11/02 15:45 | Leon U20 v Santos Laguna U20 | L | 4-3 |
| Mexico U20 League | 2020/01/19 17:00 | Santos Laguna U20 v Leon U20 | W | 2-1 |
| Mexico U20 League | 2019/08/28 14:45 | Leon U20 v Santos Laguna U20 | W | 1-2 |
| Mexico U20 League | 2019/03/02 15:45 | Leon U20 v Santos Laguna U20 | L | 2-1 |
| Mexico U20 League | 2018/09/14 16:00 | Santos Laguna U20 v Leon U20 | L | 3-4 |
Home History
| Mexico U20 League | 2021/11/18 15:00 | Leon U20 v Santos Laguna U20 | L | 1-0 |
| Mexico U20 League | 2021/11/07 17:00 | Santos Laguna U20 v Atletico San Luis U20 | W | 2-1 |
| Mexico U20 League | 2021/11/04 15:00 | Unam Pumas U20 v Santos Laguna U20 | L | 2-1 |
| Mexico U20 League | 2021/10/30 14:00 | Queretaro U20 v Santos Laguna U20 | W | 0-5 |
| Mexico U20 League | 2021/10/24 16:00 | Santos Laguna U20 v Toluca U20 | W | 3-0 |
| Mexico U20 League | 2021/10/16 17:00 | Pachuca U20 v Santos Laguna U20 | D | 2-2 |
| Mexico U20 League | 2021/10/02 15:30 | Santos Laguna U20 v Mazatlan FC U20 | W | 4-2 |
| Mexico U20 League | 2021/09/26 15:30 | Santos Laguna U20 v Monterrey U20 | W | 4-1 |
Away History
| Mexico U20 League | 2021/11/18 15:00 | Leon U20 v Santos Laguna U20 | W | 1-0 |
| Mexico U20 League | 2021/11/06 15:00 | Leon U20 v Necaxa U20 | W | 3-1 |
| Mexico U20 League | 2021/11/03 15:00 | Cruz Azul U20 v Leon U20 | L | 2-0 |
| Mexico U20 League | 2021/10/31 15:00 | Toluca U20 v Leon U20 | L | 1-0 |
| Mexico U20 League | 2021/10/23 14:00 | Puebla U20 v Leon U20 | L | 2-1 |
| Mexico U20 League | 2021/10/20 14:00 | Leon U20 v Unam Pumas U20 | L | 0-2 |
| Mexico U20 League | 2021/10/16 14:00 | Monterrey U20 v Leon U20 | D | 1-1 |
| Mexico U20 League | 2021/10/02 14:00 | Leon U20 v Atletico San Luis U20 | W | 2-0 |