| Panama Liga Prom | 2021/09/04 00:00 | SD Panama Oeste v San Francisco Reserves | L | 2-1 |
| Panama Liga Prom | 2021/05/07 20:00 | SD Panama Oeste v San Francisco Reserves | L | 4-1 |
| Panama Liga Prom | 2021/11/14 23:00 | CA Independiente de la Chorrera Reserves v San Francisco Reserves | D | 1-1 |
| Panama Liga Prom | 2021/11/07 22:00 | San Francisco Reserves v Udelas FC | W | 1-0 |
| Panama Liga Prom | 2021/10/30 21:00 | SD Atletico Nacional v San Francisco Reserves | D | 1-1 |
| Panama Liga Prom | 2021/10/22 00:00 | San Francisco Reserves v Aguilas de la U | L | 0-2 |
| Panama Liga Prom | 2021/10/17 00:00 | San Francisco Reserves v Union Cocle | W | 3-0 |
| Panama Liga Prom | 2021/10/08 23:00 | Herrera FC Reserves v San Francisco Reserves | D | 2-2 |
| Panama Liga Prom | 2021/10/03 22:00 | Atletico Chiriqui B v San Francisco Reserves | L | 2-1 |
| Panama Liga Prom | 2021/09/24 20:00 | CD Universitario Reserves v San Francisco Reserves | W | 2-4 |
| Panama Liga Prom | 2021/11/12 22:00 | SD Panama Oeste v Aguilas de la U | W | 1-0 |
| Panama Liga Prom | 2021/11/06 01:00 | CA Independiente de la Chorrera Reserves v SD Panama Oeste | D | 0-0 |
| Panama Liga Prom | 2021/10/29 20:00 | Udelas FC v SD Panama Oeste | D | 2-2 |
| Panama Liga Prom | 2021/10/21 01:00 | SD Panama Oeste v SD Atletico Nacional | W | 3-0 |
| Panama Liga Prom | 2021/10/16 22:00 | Herrera FC Reserves v SD Panama Oeste | D | 2-2 |
| Panama Liga Prom | 2021/10/09 00:29 | SD Panama Oeste v Veraguas CD Reserves | W | 1-0 |
| Panama Liga Prom | 2021/10/03 00:00 | Mario Mendez FC v SD Panama Oeste | W | 1-2 |
| Panama Liga Prom | 2021/09/25 20:00 | Union Cocle v SD Panama Oeste | W | 0-2 |