[1] Mamelodi Sundowns 2-0 Sekhukhune United [3] 2021-11-27 13:30
Stadium: Loftus Versfeld Stadium Round: 1
Home Manager: Steve Komphela Away Manager: MacDonald Makhubedu
Home History
| South Africa Premier | 2021/11/24 15:30 | Mamelodi Sundowns v Supersport United | D | 2-2 |
| South Africa Premier | 2021/11/20 15:30 | Cape Town City v Mamelodi Sundowns | D | 0-0 |
| South Africa Premier | 2021/11/07 15:30 | Marumo Gallants v Mamelodi Sundowns | W | 0-4 |
| South Africa Premier | 2021/11/03 15:30 | Mamelodi Sundowns v Maritzburg Utd | W | 1-0 |
| South Africa Supa 8 Cup | 2021/10/30 16:00 | Cape Town City v Mamelodi Sundowns | W | 3-4 |
| CAF Champions League | 2021/10/24 14:00 | Mamelodi Sundowns v AS Maniema Union | W | 2-0 |
| South Africa Premier | 2021/10/20 13:30 | Golden Arrows v Mamelodi Sundowns | W | 0-1 |
| CAF Champions League | 2021/10/17 14:00 | AS Maniema Union v Mamelodi Sundowns | D | 2-2 |
Away History
| South Africa Premier | 2021/11/20 15:30 | Sekhukhune United FC v Royal AM FC | W | 1-0 |
| South Africa Premier | 2021/11/07 13:30 | Moroka Swallows v Sekhukhune United FC | W | 0-1 |
| South Africa Premier | 2021/11/02 15:30 | Orlando Pirates v Sekhukhune United FC | L | 2-1 |
| South Africa Premier | 2021/10/27 15:30 | Sekhukhune United FC v Amazulu | W | 2-0 |
| South Africa Premier | 2021/10/16 13:30 | Sekhukhune United FC v Cape Town City | W | 1-0 |
| South Africa Premier | 2021/10/02 13:30 | TS Galaxy v Sekhukhune United FC | W | 0-1 |
| South Africa Premier | 2021/09/25 13:00 | Sekhukhune United FC v Golden Arrows | D | 1-1 |
| South Africa Premier | 2021/09/18 15:00 | Baroka FC v Sekhukhune United FC | L | 1-0 |