Stadium: Baxter Arena
Home Manager: Derrin Hansen Away Manager: Brian Barone
| NCAAB | 2021/11/27 23:00 | SIU Edwardsville v Creighton | L | 65-70 |
| NCAAB | 2021/11/21 18:00 | SIU Edwardsville v St. Thomas (MN) | L | 73-86 |
| NCAAB | 2021/11/20 19:00 | SIU Edwardsville v Youngstown State | W | 69-66 |
| NCAAB | 2021/11/20 00:45 | Niagara v SIU Edwardsville | L | 70-60 |
| NCAAB | 2021/11/16 00:00 | SIU Edwardsville v Knox | W | 75-37 |
| NCAAB | 2021/11/13 01:00 | SIU Edwardsville v Chicago St | L | 56-67 |
| NCAAB | 2021/11/10 01:30 | SIU Edwardsville v Marquette | L | 77-88 |
| NCAAB | 2021/03/04 01:00 | SIU Edwardsville v Belmont | L | 61-78 |
| NCAAB | 2021/11/26 19:00 | Nebraska Omaha v Purdue | L | 40-97 |
| NCAAB | 2021/11/24 01:00 | Nebraska Omaha v Texas Tech | L | 40-96 |
| NCAAB | 2021/11/21 02:00 | Nebraska Omaha v Montana | L | 47-68 |
| NCAAB | 2021/11/18 01:00 | Nebraska Omaha v Kansas State | L | 64-79 |
| NCAAB | 2021/11/13 17:00 | Nebraska Omaha v Ball State | L | 69-73 |
| NCAAB | 2021/11/10 00:00 | Nebraska Omaha v Hastings | W | 67-57 |
| NCAAB | 2021/03/06 23:45 | Nebraska Omaha v South Dakota State | L | 71-84 |
| NCAAB | 2021/02/27 23:00 | Nebraska Omaha v Denver | W | 80-76 |