Stadium: Gentry Complex
Home Manager: Brian Collins Away Manager: Sean Woods
| NCAAB | 2021/11/23 08:27 | Southern v Ecclesia College | W | 109-53 |
| NCAAB | 2021/11/21 21:00 | Southern v Nebraska | L | 59-82 |
| NCAAB | 2021/11/20 01:00 | Southern v South Dakota | L | 68-71 |
| NCAAB | 2021/11/17 01:00 | Southern v Rice | L | 63-81 |
| NCAAB | 2021/11/13 17:30 | Southern v Tulane | W | 73-70 |
| NCAAB | 2021/11/10 03:00 | Southern v Louisville | L | 60-72 |
| NCAAB | 2021/03/12 02:30 | Southern v Grambling State | L | 67-72 |
| NCAAB | 2021/03/06 21:00 | Southern v Texas Southern | L | 74-80 |
| NCAAB | 2021/11/24 02:00 | Tennessee State v Nebraska | L | 73-79 |
| NCAAB | 2021/11/22 01:00 | Tennessee State v South Dakota | L | 66-83 |
| NCAAB | 2021/11/17 01:00 | Tennessee State v Fisk | W | 111-56 |
| NCAAB | 2021/11/13 22:00 | Tennessee State v Norfolk State | L | 59-66 |
| NCAAB | 2021/11/10 01:00 | Tennessee State v Alabama A&M | L | 73-82 |
| NCAAB | 2021/10/27 23:00 | Tennessee State v Trevecca Nazarene | W | 76-55 |
| NCAAB | 2021/02/28 00:00 | Tennessee State v Eastern Kentucky | L | 84-89 |
| NCAAB | 2021/02/26 00:00 | Tennessee State v Morehead State | L | 60-74 |