| Italy A1 | 2021/11/24 14:00 | Metanopoli v Nuoto Catania | W | 12-9 |
| Italy A1 | 2021/11/20 15:00 | CN Posillipo v Metanopoli | L | 10-7 |
| Italy A1 | 2021/11/13 16:00 | Metanopoli v SS Lazio | W | 13-11 |
| Italy A1 | 2021/11/06 13:00 | CC Ortigia v Metanopoli | L | 15-5 |
| Italy A1 | 2021/10/30 13:00 | Metanopoli v Pro Recco | L | 4-21 |
| Italy A1 | 2021/10/23 13:00 | R.N. Salerno v Metanopoli | L | 13-8 |
| Italy A1 | 2021/10/13 18:15 | Metanopoli v AN Brescia | L | 5-16 |
| Italy A1 | 2021/10/05 14:00 | Telimar v Metanopoli | L | 12-7 |
| Italy A1 | 2021/11/24 15:30 | Anzio v AN Brescia | L | 6-18 |
| Italy A1 | 2021/11/20 15:00 | Nuoto Catania v Anzio | W | 6-8 |
| Italy A1 | 2021/11/13 14:00 | Anzio v Telimar | L | 10-12 |
| Italy A1 | 2021/11/06 14:00 | CN Posillipo v Anzio | W | 9-12 |
| Italy A1 | 2021/10/30 14:30 | Anzio v Roma Nuoto | D | 7-7 |
| Italy A1 | 2021/10/23 13:30 | SS Lazio v Anzio | D | 9-9 |
| Italy A1 | 2021/10/16 14:30 | Anzio v SC Quinto | W | 10-9 |
| Italy A1 | 2021/10/06 13:00 | CC Ortigia v Anzio | L | 17-9 |