[12] Real Santa Cruz 1-1 Nacional Potosi [10] 2021-12-01 19:00
Stadium: Estadio Juan Carlos Duran Round: 28
Head to Head
| Bolivia Apertura | 2021/08/03 22:15 | Nacional Potosi v Real Santa Cruz | D | 2-2 |
| Bolivia Apertura | 2020/12/27 19:00 | Nacional Potosi v Real Santa Cruz | L | 1-0 |
| Bolivia Apertura | 2020/03/06 19:00 | Real Santa Cruz v Nacional Potosi | W | 2-1 |
Home History
| Bolivia Apertura | 2021/11/27 23:30 | Independiente Petrolero v Real Santa Cruz | L | 2-1 |
| Bolivia Clausura | 2021/11/22 19:45 | San Jose v Real Santa Cruz | W | 1-2 |
| Bolivia Apertura | 2021/11/07 19:00 | Club Aurora v Real Santa Cruz | L | 4-1 |
| Bolivia Apertura | 2021/11/01 19:00 | Real Santa Cruz v Real Tomayapo | W | 2-0 |
| Bolivia Apertura | 2021/10/24 23:30 | Real Santa Cruz v Bolivar | L | 0-3 |
| Bolivia Apertura | 2021/10/17 23:30 | Blooming v Real Santa Cruz | L | 3-1 |
| Bolivia Apertura | 2021/09/27 19:00 | Real Santa Cruz v Guabira | W | 3-0 |
| Bolivia Apertura | 2021/09/21 23:00 | Real Potosi v Real Santa Cruz | L | 3-0 |
Away History
| Bolivia Clausura | 2021/11/26 19:00 | Nacional Potosi v San Jose | W | 7-1 |
| Bolivia Apertura | 2021/11/23 00:00 | Real Tomayapo v Nacional Potosi | L | 3-0 |
| Bolivia Apertura | 2021/10/31 21:15 | Nacional Potosi v Club Aurora | D | 0-0 |
| Bolivia Apertura | 2021/10/28 22:15 | Bolivar v Nacional Potosi | L | 4-2 |
| Bolivia Apertura | 2021/10/23 23:30 | Nacional Potosi v Blooming | W | 4-0 |
| Bolivia Apertura | 2021/10/18 19:00 | Guabira v Nacional Potosi | L | 3-2 |
| Bolivia Apertura | 2021/09/26 19:00 | Nacional Potosi v Real Potosi | W | 4-2 |
| Bolivia Apertura | 2021/09/23 21:15 | Royal Pari FC v Nacional Potosi | L | 2-0 |