Prairie View A&M 10-27 Jackson State 2021-12-04 21:00
Stadium: Mississippi Veterans Memorial Stadium Round: 1
Home Manager: Deion Sanders Away Manager: Eric Dooley
Head to Head
| NCAAF | 2019/10/24 23:30 | Jackson State v Prairie View | L | 38-35 |
| NCAAF FCS | 2018/11/03 19:00 | Prairie View v Jackson State | L | 28-34 |
| NCAAF | 2017/09/30 21:00 | Prairie View v Jackson State | W | 38-9 |
Home History
| NCAAF | 2021/11/27 20:00 | Mississippi Valley State v Prairie View | L | 24-19 |
| NCAAF | 2021/11/20 17:00 | Prairie View v Texas A&M | L | 3-52 |
| NCAAF | 2021/11/13 20:00 | Prairie View v Alcorn State | L | 29-31 |
| NCAAF | 2021/11/06 19:00 | Alabama State v Prairie View | W | 20-24 |
| NCAAF | 2021/10/23 23:00 | Prairie View v Southern | W | 48-21 |
| NCAAF | 2021/10/16 17:00 | Prairie View v Bethune Cookman | W | 35-29 |
| NCAAF | 2021/09/30 23:30 | Arkansas Pine Bluff v Prairie View | W | 17-27 |
| NCAAF | 2021/09/25 21:00 | Grambling State v Prairie View | W | 10-24 |
Away History
| NCAAF | 2021/11/20 19:00 | Alcorn State v Jackson State | W | 10-24 |
| NCAAF | 2021/11/14 00:00 | Jackson State v Southern | W | 21-17 |
| NCAAF | 2021/11/06 18:00 | Texas Southern Tigers v Jackson State | W | 21-41 |
| NCAAF | 2021/10/30 20:00 | Jackson State v Mississippi Valley State | W | 28-19 |
| NCAAF | 2021/10/23 18:00 | Bethune Cookman v Jackson State | W | 12-42 |
| NCAAF | 2021/10/16 19:00 | Alabama State v Jackson State | W | 7-28 |
| NCAAF | 2021/10/09 19:00 | Jackson State v Alabama | W | 61-15 |
| NCAAF | 2021/09/25 19:00 | Jackson State v Delta State | W | 24-17 |