Western Kentucky 41-49 Texas San Antonio 2021-12-04 00:00
Stadium: Alamodome Round: 1
Home Manager: Jeff Traylor Away Manager: Tyson Helton
Head to Head
| NCAAF | 2021/10/09 23:00 | Texas-San Antonio v Western Kentucky | L | 52-46 |
| NCAAF | 2014/11/22 17:00 | Western Kentucky v Texas-San Antonio | W | 45-7 |
Home History
| NCAAF | 2021/11/27 20:30 | Western Kentucky v Marshall | W | 53-21 |
| NCAAF | 2021/11/20 17:00 | Florida Atlantic v Western Kentucky | W | 17-52 |
| NCAAF | 2021/11/13 19:00 | Western Kentucky v Rice | W | 42-21 |
| NCAAF | 2021/11/06 19:30 | Middle Tennessee St. v Western Kentucky | W | 21-48 |
| NCAAF | 2021/10/30 20:00 | Charlotte v Western Kentucky | W | 13-45 |
| NCAAF | 2021/10/23 23:00 | Western Kentucky v Florida Intl | W | 34-19 |
| NCAAF | 2021/10/16 19:30 | Western Kentucky v Old Dominion | W | 43-20 |
| NCAAF | 2021/10/09 23:00 | Texas-San Antonio v Western Kentucky | L | 52-46 |
Away History
| NCAAF | 2021/11/27 19:00 | Texas-San Antonio v North Texas | L | 23-45 |
| NCAAF | 2021/11/20 20:30 | UAB v Texas-San Antonio | W | 31-34 |
| NCAAF | 2021/11/13 20:30 | Southern Mississippi v Texas-San Antonio | W | 17-27 |
| NCAAF | 2021/11/07 02:15 | Texas-San Antonio v UTEP | W | 44-23 |
| NCAAF | 2021/10/23 23:00 | Texas-San Antonio v Louisiana Tech | W | 45-16 |
| NCAAF | 2021/10/16 22:00 | Rice v Texas-San Antonio | W | 0-45 |
| NCAAF | 2021/10/09 23:00 | Texas-San Antonio v Western Kentucky | W | 52-46 |
| NCAAF | 2021/10/02 22:00 | UNLV v Texas-San Antonio | W | 17-24 |