Home History
| NFL | 2016/10/07 00:25 | ARZ Cardinals v SF 49ers | L | 33-21 |
| NFL | 2016/10/02 20:25 | DAL Cowboys v SF 49ers | L | 24-17 |
| NFL | 2016/09/25 20:05 | SF 49ers v SEA Seahawks | L | 18-37 |
| NFL | 2016/09/18 17:00 | SF 49ers v CAR Panthers | L | 27-46 |
| NFL | 2016/09/13 02:20 | LA Rams v SF 49ers | W | 0-28 |
| NFL Preseason | 2016/09/02 02:00 | LA Chargers v SF 49ers | W | 21-31 |
| NFL Preseason | 2016/08/27 02:00 | SF 49ers v GB Packers | L | 10-21 |
| NFL Preseason | 2016/08/21 01:00 | DEN Broncos v SF 49ers | W | 24-31 |
Away History
| NFL | 2016/10/09 20:25 | BUF Bills v LA Rams | W | 30-19 |
| NFL | 2016/10/02 17:00 | BUF Bills v NE Patriots | W | 16-0 |
| NFL | 2016/09/25 17:00 | ARZ Cardinals v BUF Bills | W | 18-33 |
| NFL | 2016/09/16 00:25 | NY Jets v BUF Bills | L | 37-31 |
| NFL | 2016/09/11 17:00 | BUF Bills v BAL Ravens | L | 7-13 |
| NFL Preseason | 2016/09/01 23:30 | DET Lions v BUF Bills | L | 31-0 |
| NFL Preseason | 2016/08/20 20:00 | BUF Bills v NY Giants | W | 21-0 |
| NFL Preseason | 2016/08/13 23:00 | BUF Bills v IND Colts | L | 18-19 |