Stadium: Benedetti–Wehrli Stadium Round: 2
| NCAAF | 2021/12/04 18:00 | North Central Illinois v Rpi Engineers | W | 55-6 |
| NCAAF | 2021/11/27 18:00 | North Central Illinois v Uw-La Crosse Eagles | W | 34-20 |
| NCAAF | 2021/11/13 18:00 | North Central Illinois v North Park Vikings | W | 84-6 |
| NCAAF | 2021/11/06 17:00 | Washington Bears v North Central Illinois | W | 20-59 |
| NCAAF | 2021/10/30 23:00 | Millikin Big Blue v North Central Illinois | W | 27-54 |
| NCAAF | 2021/10/23 23:00 | North Central Illinois v Illinois Wesleyan Titans | W | 55-7 |
| NCAAF | 2021/10/16 23:00 | North Central Illinois v Elmhurst Bluejays | W | 77-7 |
| NCAAF | 2021/10/09 17:00 | Carthage Red Men v North Central Illinois | W | 13-64 |
| NCAAF | 2021/12/04 17:00 | Mount Union v Muhlenberg Mules | W | 35-29 |
| NCAAF | 2021/11/27 17:00 | Mount Union v Johns Hopkins Blue Jays | W | 45-35 |
| NCAAF | 2021/11/20 17:00 | Mount Union v Washington And Lee Generals | W | 52-0 |
| NCAAF | 2021/11/13 18:30 | Marietta Pioneers v Mount Union | W | 7-37 |
| NCAAF | 2021/11/06 17:30 | Mount Union v Muskingum Muskies | W | 73-7 |
| NCAAF | 2021/10/30 18:00 | Mount Union v Ohio Northern Polar Bears | W | 42-35 |
| NCAAF | 2021/10/23 17:30 | Heidelberg Student Princes v Mount Union | W | 14-49 |
| NCAAF | 2021/10/16 17:30 | Mount Union v Capital Crusaders | W | 63-0 |