Toledo 24-31 Middle Tennessee 2021-12-17 17:00
Stadium: Thomas Robinson Stadium Round: 288
Home Manager: Jason Candle Away Manager: Rick Stockstill
Home History
| NCAAF | 2021/11/27 17:00 | Akron v Toledo | W | 14-49 |
| NCAAF | 2021/11/17 00:00 | Toledo v Ohio | W | 35-23 |
| NCAAF | 2021/11/11 00:00 | Toledo v Bowling Green | W | 49-17 |
| NCAAF | 2021/11/02 23:30 | Eastern Michigan v Toledo | L | 52-49 |
| NCAAF | 2021/10/23 19:30 | Western Michigan v Toledo | W | 15-34 |
| NCAAF | 2021/10/16 19:30 | Toledo v Central Michigan | L | 23-26 |
| NCAAF | 2021/10/09 16:00 | Northern Illinois v Toledo | L | 22-20 |
| NCAAF | 2021/10/02 16:00 | Toledo v Massachusetts | W | 45-7 |
Away History
| NCAAF | 2021/11/28 00:00 | Middle Tennessee St. v Florida Atlantic | W | 27-17 |
| NCAAF | 2021/11/20 20:30 | Old Dominion v Middle Tennessee St. | L | 24-17 |
| NCAAF | 2021/11/13 20:30 | Florida Intl v Middle Tennessee St. | W | 10-50 |
| NCAAF | 2021/11/06 19:30 | Middle Tennessee St. v Western Kentucky | L | 21-48 |
| NCAAF | 2021/10/30 19:30 | Southern Mississippi v Middle Tennessee St. | W | 10-35 |
| NCAAF | 2021/10/22 22:00 | Middle Tennessee St. v Connecticut | W | 44-13 |
| NCAAF | 2021/10/09 19:30 | Middle Tennessee St. v Liberty | L | 13-41 |
| NCAAF | 2021/10/02 23:00 | Marshall v Middle Tennessee St. | W | 28-34 |