Stadium: Ram Stadium Round: 8
| NCAAF | 2021/11/20 17:00 | Shepherd Rams v Findlay Oilers | W | 38-31 |
| NCAAF | 2021/11/06 16:00 | Shepherd Rams v East Stroudsburg Warriors | W | 55-7 |
| NCAAF | 2021/10/30 18:00 | Bloomsburg Huskies v Shepherd Rams | W | 18-62 |
| NCAAF | 2021/10/23 16:00 | Shepherd Rams v West Chester Golden Rams | W | 42-38 |
| NCAAF | 2021/10/16 18:00 | Millersville University of Pennsylvania Marauders v Shepherd Rams | W | 13-38 |
| NCAAF | 2021/10/09 17:00 | Lock Haven v Shepherd Rams | W | 21-75 |
| NCAAF | 2021/10/02 16:00 | Shepherd Rams v Shippensburg Raiders | W | 59-27 |
| NCAAF | 2021/09/25 16:00 | Shepherd Rams v Kutztown Golden Bears | L | 29-37 |
| NCAAF | 2021/11/20 17:00 | Notre Dame Falcons v Slippery Rock | W | 33-25 |
| NCAAF | 2021/11/13 17:00 | Notre Dame Falcons v Alderson Broaddus Battlers | W | 72-7 |
| NCAAF | 2021/11/06 16:00 | Unc Pembroke Braves v Notre Dame Falcons | W | 7-45 |
| NCAAF | 2021/10/30 16:00 | Notre Dame Falcons v Fairmont State | W | 45-0 |
| NCAAF | 2021/10/23 17:30 | Glenville State Pioneers v Notre Dame Falcons | W | 14-34 |
| NCAAF | 2021/10/16 17:00 | Notre Dame Falcons v W. Virginia Bobcats | W | 52-14 |
| NCAAF | 2021/10/09 16:00 | Notre Dame Falcons v Frostburg State | W | 23-21 |
| NCAAF | 2021/10/02 16:00 | University of Charleston Golden Eagles v Notre Dame Falcons | L | 38-28 |