Stadium: Crusader Stadium Round: 8
| NCAAF | 2021/11/20 18:00 | Mary Hardin Baylor v Trinity Tigers | W | 13-3 |
| NCAAF | 2021/11/13 19:00 | Mcmurry Warhawks v Mary Hardin Baylor | W | 3-77 |
| NCAAF | 2021/11/06 18:00 | Mary Hardin Baylor v Howard Payne Yellow Jackets | W | 59-14 |
| NCAAF | 2021/10/30 17:00 | Mary Hardin Baylor v Belhaven Blazers | W | 29-0 |
| NCAAF | 2021/10/23 18:00 | Sul Ross State Lobos v Mary Hardin Baylor | W | 14-72 |
| NCAAF | 2021/10/16 18:00 | Mary Hardin Baylor v Texas Lutheran Bulldogs | W | 49-3 |
| NCAAF | 2021/10/02 18:00 | Austin Kangaroos v Mary Hardin Baylor | W | 0-56 |
| NCAAF | 2021/09/25 23:00 | Mary Hardin Baylor v Hardin Simmons Cowboys | W | 34-28 |
| NCAAF | 2021/11/20 18:00 | Birmingham Southern Panthers v Huntingdon Hawks | W | 24-14 |
| NCAAF | 2021/11/13 19:00 | Millsaps Majors v Birmingham Southern Panthers | W | 7-49 |
| NCAAF | 2021/11/06 17:00 | Birmingham Southern Panthers v Trinity Tigers | L | 27-28 |
| NCAAF | 2021/10/30 19:00 | Berry Vikings v Birmingham Southern Panthers | W | 3-21 |
| NCAAF | 2021/10/23 21:30 | Birmingham Southern Panthers v Rhodes Lynx | W | 41-6 |
| NCAAF | 2021/10/16 17:00 | Centre Colonels v Birmingham Southern Panthers | W | 21-28 |
| NCAAF | 2021/10/09 18:00 | Hendrix Warriors v Birmingham Southern Panthers | W | 6-43 |
| NCAAF | 2021/10/02 23:00 | Birmingham Southern Panthers v Sewanee Tigers | W | 49-0 |