Stadium: Perkins Stadium at a Glance Round: 8
| NCAAF | 2021/11/20 18:00 | UW-Whitewater v Greenville Panthers | W | 69-7 |
| NCAAF | 2021/11/13 19:00 | Uw-Stevens Point Pointers v UW-Whitewater | W | 10-56 |
| NCAAF | 2021/11/06 18:00 | UW-Whitewater v Uw-La Crosse Eagles | W | 13-7 |
| NCAAF | 2021/10/30 18:00 | UW-Whitewater v Uw-Eau Claire Blugolds | W | 48-6 |
| NCAAF | 2021/10/23 18:00 | Uw-River Falls Falcons v UW-Whitewater | W | 28-34 |
| NCAAF | 2021/10/16 18:00 | Wisconsin Oshkosh v UW-Whitewater | W | 13-32 |
| NCAAF | 2021/10/09 18:00 | UW-Whitewater v Uw-Platteville Pioneers | W | 65-21 |
| NCAAF | 2021/10/02 19:00 | UW-Whitewater v Uw-Stout Blue Devils | W | 37-6 |
| NCAAF | 2021/11/20 17:00 | Depauw Tigers v Rose Hulman Engineers | W | 26-21 |
| NCAAF | 2021/11/13 18:07 | Wabash Little Giants v Depauw Tigers | L | 42-35 |
| NCAAF | 2021/11/06 17:00 | Depauw Tigers v Oberlin Yeomen | W | 66-13 |
| NCAAF | 2021/10/30 17:00 | Depauw Tigers v Denison Big Red | W | 27-10 |
| NCAAF | 2021/10/23 17:00 | Allegheny Gators v Depauw Tigers | W | 14-38 |
| NCAAF | 2021/10/16 17:00 | Depauw Tigers v Ohio Wesleyan Battling Bishops | W | 24-7 |
| NCAAF | 2021/10/09 18:00 | Wittenberg Tigers v Depauw Tigers | W | 14-17 |
| NCAAF | 2021/10/02 17:00 | Depauw Tigers v Hiram Terriers | W | 57-7 |