Stadium: SUNY Cortland Stadium Complex Round: 8
| NCAAF | 2021/11/20 17:00 | Cortland Red Dragons v Springfield Pride | W | 26-21 |
| NCAAF | 2021/11/13 17:00 | Ithaca Bombers v Cortland Red Dragons | L | 28-27 |
| NCAAF | 2021/11/06 17:00 | St John Fisher Cardinals v Cortland Red Dragons | W | 3-55 |
| NCAAF | 2021/10/30 17:00 | Cortland Red Dragons v Alfred Saxons | W | 47-3 |
| NCAAF | 2021/10/23 17:00 | Cortland Red Dragons v Utica Pioneers | W | 45-0 |
| NCAAF | 2021/10/16 17:00 | Hartwick Hawks v Cortland Red Dragons | W | 3-48 |
| NCAAF | 2021/10/09 16:00 | Cortland Red Dragons v Brockport Golden Eagles | W | 31-10 |
| NCAAF | 2021/10/02 17:00 | Morrisville State Mustangs v Cortland Red Dragons | W | 7-58 |
| NCAAF | 2021/11/20 17:00 | Endicott Gulls v Rpi Engineers | W | 14-20 |
| NCAAF | 2021/11/13 17:00 | Union Dutchmen v Rpi Engineers | W | 17-19 |
| NCAAF | 2021/11/13 16:00 | Union College Bulldogs v Rpi Engineers | W | 17-19 |
| NCAAF | 2021/11/06 17:00 | St Lawrence Saints v Rpi Engineers | W | 20-22 |
| NCAAF | 2021/10/30 16:00 | Rpi Engineers v Ithaca Bombers | W | 14-11 |
| NCAAF | 2021/10/16 17:00 | Hobart Statesmen v Rpi Engineers | L | 10-9 |
| NCAAF | 2021/10/09 16:00 | Rpi Engineers v Buffalo State Bengals | W | 24-16 |
| NCAAF | 2021/10/02 16:00 | Rpi Engineers v Rochester Yellowjackets | W | 38-22 |