Stadium: Harrison HPER Complex
Home Manager: Lindsey Hunter Away Manager: Austin Claunch
| NCAAB | 2021/11/27 19:00 | Nicholls State v Southwestern Christian Eagles | W | 87-58 |
| NCAAB | 2021/11/24 22:30 | Nicholls State v Utah Valley | L | 63-74 |
| NCAAB | 2021/11/22 20:00 | Cal Poly SLO v Nicholls State | W | 72-75 |
| NCAAB | 2021/11/19 01:00 | Nicholls State v TCU | L | 50-63 |
| NCAAB | 2021/11/15 17:00 | Nicholls State v Baylor Bears | L | 60-89 |
| NCAAB | 2021/11/13 18:00 | Nicholls State v Carver | W | 101-44 |
| NCAAB | 2021/11/13 01:00 | Nicholls State v Carver | W | 120-52 |
| NCAAB | 2021/11/10 01:00 | Nicholls State v Northern Iowa | W | 62-58 |
| NCAAB | 2021/12/05 01:00 | Mississippi Valley State v Grand Canyon | L | 44-91 |
| NCAAB | 2021/12/02 02:00 | Mississippi Valley State v North Alabama | L | 58-72 |
| NCAAB | 2021/11/30 01:00 | Mississippi Valley State v Vanderbilt | L | 36-75 |
| NCAAB | 2021/11/26 21:00 | Mississippi Valley State v Mississippi | L | 58-73 |
| NCAAB | 2021/11/14 03:00 | Mississippi Valley State v California Baptist | L | 66-95 |
| NCAAB | 2021/11/10 00:45 | Mississippi Valley State v St Johns | L | 61-119 |
| NCAAB | 2021/03/11 02:30 | Mississippi Valley State v Prairie View | L | 64-91 |
| NCAAB | 2021/03/06 01:00 | Arkansas-Pine Bluff v Mississippi Valley State | L | 82-59 |