Stadium: F. G. Clark Center
Home Manager: Sean Woods Away Manager: Johnny Jones
| NCAAB | 2021/03/06 21:00 | Southern v Texas Southern | W | 74-80 |
| NCAAB | 2020/03/06 01:30 | Texas Southern v Southern | L | 74-89 |
| NCAAB | 2020/01/05 01:30 | Southern v Texas Southern | W | 68-77 |
| NCAAB | 2019/03/13 00:30 | Southern v Texas Southern | W | 70-80 |
| NCAAB | 2019/03/10 01:30 | Southern v Texas Southern | L | 87-77 |
| NCAAB | 2019/01/08 01:30 | Texas Southern v Southern | W | 77-67 |
| NCAAB | 2018/03/02 01:30 | Southern v Texas Southern | W | 88-90 |
| NCAAB | 2018/01/02 02:00 | Southern v Texas Southern | W | 66-78 |
| NCAAB | 2021/12/15 01:30 | Texas Southern v UT-Rio Grande Valley | W | 70-60 |
| NCAAB | 2021/12/06 23:00 | Texas Southern v Florida Gators | W | 69-54 |
| NCAAB | 2021/12/02 00:30 | Texas Southern v Louisiana Tech | L | 60-87 |
| NCAAB | 2021/11/25 02:00 | Texas Southern v BYU | L | 64-81 |
| NCAAB | 2021/11/21 23:00 | Texas Southern v NC State | L | 57-65 |
| NCAAB | 2021/11/18 02:00 | Texas Southern v Air Force | L | 57-61 |
| NCAAB | 2021/11/16 02:00 | Texas Southern v Washington | L | 65-72 |
| NCAAB | 2021/11/13 03:00 | Texas Southern v Saint Mary's CA | L | 58-67 |
| NCAAB | 2021/12/22 00:00 | Southern v Dayton | L | 60-69 |
| NCAAB | 2021/12/19 22:30 | Southern v Kent State | W | 78-76 |
| NCAAB | 2021/12/11 23:30 | SE Louisiana v Southern | W | 66-72 |
| NCAAB | 2021/12/10 01:00 | Southern v Lindsey Wilson College | W | 86-68 |
| NCAAB | 2021/12/08 00:00 | Southern v Kentucky | L | 64-76 |
| NCAAB | 2021/12/05 00:00 | Southern v Akron | L | 62-79 |
| NCAAB | 2021/11/28 20:00 | Southern v Tennessee State | W | 82-80 |
| NCAAB | 2021/11/23 08:27 | Southern v Ecclesia College | W | 109-53 |