[6] BUF Sabres 1-6 EDM Oilers [3] 2022-03-18 01:00
Stadium: Rogers Place
Home Manager: Jay Woodcroft Away Manager: Don Granato
Head to Head
| NHL | 2021/11/13 00:00 | EDM Oilers v BUF Sabres | W | 2-3 |
| NHL | 2020/01/03 00:00 | EDM Oilers v BUF Sabres | W | 2-3 |
| NHL | 2019/12/09 01:00 | BUF Sabres v EDM Oilers | W | 3-2 |
| NHL | 2019/03/05 00:00 | EDM Oilers v BUF Sabres | L | 4-3 |
| NHL | 2019/01/15 02:00 | BUF Sabres v EDM Oilers | L | 2-7 |
| NHL | 2018/01/24 02:00 | BUF Sabres v EDM Oilers | W | 5-0 |
| NHL | 2017/11/25 00:00 | EDM Oilers v BUF Sabres | W | 1-3 |
| NHL | 2016/12/07 00:00 | EDM Oilers v BUF Sabres | W | 3-4 |
Home History
| NHL | 2022/03/13 20:00 | TOR Maple Leafs v BUF Sabres | W | 2-5 |
| NHL | 2022/03/11 00:00 | VGS Golden Knights v BUF Sabres | W | 1-3 |
| NHL | 2022/03/08 00:00 | FLA Panthers v BUF Sabres | L | 6-1 |
| NHL | 2022/03/06 18:00 | LA Kings v BUF Sabres | L | 3-0 |
| NHL | 2022/03/05 00:00 | MIN Wild v BUF Sabres | W | 4-5 |
| NHL | 2022/03/03 00:30 | BUF Sabres v TOR Maple Leafs | W | 5-1 |
| NHL | 2022/02/27 19:00 | BUF Sabres v DAL Stars | L | 2-4 |
| NHL | 2022/02/26 01:00 | BUF Sabres v STL Blues | L | 3-5 |
Away History
| NHL | 2022/03/16 01:00 | DET Red Wings v EDM Oilers | W | 5-7 |
| NHL | 2022/03/13 03:00 | TB Lightning v EDM Oilers | W | 1-4 |
| NHL | 2022/03/10 01:00 | WAS Capitals v EDM Oilers | W | 3-4 |
| NHL | 2022/03/08 02:30 | EDM Oilers v CAL Flames | L | 1-3 |
| NHL | 2022/03/06 00:00 | MON Canadiens v EDM Oilers | L | 5-2 |
| NHL | 2022/03/04 01:30 | EDM Oilers v CHI Blackhawks | L | 3-4 |
| NHL | 2022/03/02 00:00 | EDM Oilers v PHI Flyers | W | 3-0 |
| NHL | 2022/02/27 18:00 | EDM Oilers v CAR Hurricanes | L | 1-2 |