Stadium: Winthrop Coliseum
Home Manager: Mark Prosser Away Manager: Ryan Saunders
| NCAAB | 2021/12/22 00:00 | Winthrop v Mississippi State | L | 63-84 |
| NCAAB | 2021/12/16 00:00 | Winthrop v Elon | L | 61-63 |
| NCAAB | 2021/12/12 00:00 | Winthrop v Carver | W | 83-52 |
| NCAAB | 2021/12/08 00:00 | Furman v Winthrop | W | 80-85 |
| NCAAB | 2021/12/04 18:00 | Winthrop v Coastal Carolina | L | 64-74 |
| NCAAB | 2021/12/02 00:30 | Hartford v Winthrop | W | 75-82 |
| NCAAB | 2021/11/28 03:00 | Winthrop v Washington | W | 82-74 |
| NCAAB | 2021/11/23 02:00 | Winthrop v Washington State | L | 86-92 |
| NCAAB | 2021/12/18 21:00 | USC Upstate v Converse Valkyries | L | 78-38 |
| NCAAB | 2021/12/18 00:00 | Gardner Webb v Converse Valkyries | L | 79-46 |