Head to Head
| Mexico U20 League | 2021/11/04 15:00 | Unam Pumas U20 v Santos Laguna U20 | L | 2-1 |
| Mexico U20 League | 2021/03/04 15:00 | Unam Pumas U20 v Santos Laguna U20 | D | 0-0 |
| Mexico U20 League | 2020/09/09 16:00 | Santos Laguna U20 v Unam Pumas U20 | L | 1-3 |
| Mexico U20 League | 2020/02/01 17:00 | Santos Laguna U20 v Unam Pumas U20 | W | 2-0 |
| Mexico U20 League | 2019/09/29 14:00 | Unam Pumas U20 v Santos Laguna U20 | L | 2-1 |
| Mexico U20 League | 2019/05/05 16:00 | Santos Laguna U20 v Unam Pumas U20 | D | 1-1 |
| Mexico U20 League | 2018/11/25 15:00 | Unam Pumas U20 v Santos Laguna U20 | L | 4-0 |
| Mexico U20 League | 2018/05/06 15:00 | Unam Pumas U20 v Santos Laguna U20 | L | 4-1 |
Home History
| Mexico U20 League | 2022/02/27 15:00 | Cruz Azul U20 v Santos Laguna U20 | L | 2-1 |
| Mexico U20 League | 2022/02/18 16:00 | FC Juarez U20 v Santos Laguna U20 | W | 1-2 |
| Mexico U20 League | 2022/02/12 17:00 | Santos Laguna U20 v Club America U20 | D | 0-0 |
| Mexico U20 League | 2022/02/06 15:00 | Atlas U20 v Santos Laguna U20 | W | 0-1 |
| Mexico U20 League | 2022/01/23 17:00 | Santos Laguna U20 v Necaxa U20 | L | 0-3 |
| Mexico U20 League | 2022/01/16 15:00 | Toluca U20 v Santos Laguna U20 | L | 4-2 |
| Mexico U20 League | 2022/01/12 17:00 | Santos Laguna U20 v Tigres U20 | L | 1-3 |
| Mexico U20 League | 2021/12/05 17:00 | Santos Laguna U20 v Cruz Azul U20 | W | 3-0 |
Away History
| Mexico U20 League | 2022/02/26 15:00 | Unam Pumas U20 v Club America U20 | L | 0-1 |
| Mexico U20 League | 2022/02/20 15:00 | Atlas U20 v Unam Pumas U20 | D | 0-0 |
| Mexico U20 League | 2022/02/13 15:00 | Unam Pumas U20 v Leon U20 | W | 2-1 |
| Mexico U20 League | 2022/02/05 23:45 | Tijuana U20 v Unam Pumas U20 | D | 1-1 |
| Mexico U20 League | 2022/01/27 15:00 | Unam Pumas U20 v Monterrey U20 | W | 4-0 |
| Mexico U20 League | 2022/01/23 15:00 | Unam Pumas U20 v Tigres U20 | W | 2-1 |
| Mexico U20 League | 2022/01/14 15:00 | Queretaro U20 v Unam Pumas U20 | W | 0-1 |
| Mexico U20 League | 2022/01/09 15:00 | Unam Pumas U20 v Toluca U20 | D | 1-1 |