Head to Head
| Mexico U20 League | 2021/11/21 17:00 | Santos Laguna U20 v Leon U20 | W | 1-0 |
| Mexico U20 League | 2021/11/18 15:00 | Leon U20 v Santos Laguna U20 | L | 1-0 |
| Mexico U20 League | 2021/08/21 14:00 | Leon U20 v Santos Laguna U20 | D | 1-1 |
| Mexico U20 League | 2021/03/21 17:00 | Santos Laguna U20 v Leon U20 | W | 3-0 |
| Mexico U20 League | 2020/11/02 15:45 | Leon U20 v Santos Laguna U20 | L | 4-3 |
| Mexico U20 League | 2020/01/19 17:00 | Santos Laguna U20 v Leon U20 | W | 2-1 |
| Mexico U20 League | 2019/08/28 14:45 | Leon U20 v Santos Laguna U20 | W | 1-2 |
| Mexico U20 League | 2019/03/02 15:45 | Leon U20 v Santos Laguna U20 | L | 2-1 |
Home History
| Mexico U20 League | 2022/04/19 15:00 | Mazatlan FC U20 v Santos Laguna U20 | W | 1-2 |
| Mexico U20 League | 2022/04/16 16:00 | Santos Laguna U20 v Queretaro U20 | D | 2-2 |
| Mexico U20 League | 2022/04/03 16:00 | Santos Laguna U20 v Pachuca U20 | W | 1-0 |
| Mexico U20 League | 2022/03/26 15:00 | Monterrey U20 v Santos Laguna U20 | W | 1-2 |
| Mexico U20 League | 2022/03/18 15:00 | Puebla U20 v Santos Laguna U20 | W | 0-1 |
| Mexico U20 League | 2022/03/12 17:00 | Santos Laguna U20 v Tijuana U20 | W | 4-2 |
| Mexico U20 League | 2022/03/05 15:00 | Chivas Guadalajara U20 v Santos Laguna U20 | D | 0-0 |
| Mexico U20 League | 2022/03/02 17:00 | Santos Laguna U20 v Unam Pumas U20 | W | 2-1 |
Away History
| Mexico U20 League | 2022/04/20 14:00 | Club America U20 v Leon U20 | L | 2-1 |
| Mexico U20 League | 2022/04/16 14:00 | Leon U20 v Puebla U20 | W | 4-1 |
| Mexico U20 League | 2022/04/09 14:00 | Atletico San Luis U20 v Leon U20 | D | 1-1 |
| Mexico U20 League | 2022/04/03 14:00 | Leon U20 v Queretaro U20 | W | 2-1 |
| Mexico U20 League | 2022/03/18 16:00 | Mazatlan FC U20 v Leon U20 | L | 1-0 |
| Mexico U20 League | 2022/03/12 15:00 | Leon U20 v Tigres U20 | W | 2-1 |
| Mexico U20 League | 2022/03/04 16:00 | FC Juarez U20 v Leon U20 | W | 0-1 |
| Mexico U20 League | 2022/03/01 15:00 | Leon U20 v Monterrey U20 | L | 1-2 |