Stadium: Knapp Center
Home Manager: Darian DeVries Away Manager: Gerald Gillion
| NCAAB | 2020/12/20 20:00 | Chicago St v Drake | L | 67-111 |
| NCAAB | 2017/11/26 20:00 | Drake v Chicago St | L | 79-67 |
| NCAAB | 2010/12/23 12:00 | Drake v Chicago St | L | 102-51 |
| NCAAB | 2007/12/07 12:00 | Drake v Chicago St | L | 83-53 |
| NCAAB | 2021/12/22 00:00 | Chicago St v Iowa State | L | 48-79 |
| NCAAB | 2021/12/17 00:00 | Chicago St v IU Indianapolis | W | 61-55 |
| NCAAB | 2021/12/13 18:00 | Northern Illinois v Chicago St | L | 70-59 |
| NCAAB | 2021/12/11 20:00 | Illinois St v Chicago St | L | 81-71 |
| NCAAB | 2021/12/04 22:00 | Tennessee State v Chicago St | W | 49-59 |
| NCAAB | 2021/12/02 00:00 | Chicago St v Loyola Maryland | L | 64-78 |
| NCAAB | 2021/11/28 19:00 | Chicago St v Bowling Green | L | 57-75 |
| NCAAB | 2021/11/23 03:00 | Chicago St v Pacific | L | 58-74 |
| NCAAB | 2021/12/19 20:00 | Tennessee Martin v Drake | W | 54-80 |
| NCAAB | 2021/12/17 01:00 | Jackson State v Drake | W | 65-70 |
| NCAAB | 2021/12/11 19:00 | Drake v Clemson | L | 80-90 |
| NCAAB | 2021/12/09 02:00 | Drake v Nebraska Omaha | W | 78-70 |
| NCAAB | 2021/12/05 20:00 | St. Thomas (MN) v Drake | W | 64-74 |
| NCAAB | 2021/12/03 02:00 | Valparaiso v Drake | W | 66-73 |
| NCAAB | 2021/11/28 15:30 | North Texas v Drake | L | 57-54 |
| NCAAB | 2021/11/26 21:30 | Alabama v Drake | L | 80-71 |