Head to Head
| Mexico Liga MX Femenil | 2021/10/09 21:00 | Toluca Women v Santos Laguna Women | L | 1-0 |
| Mexico Liga MX Femenil | 2021/04/19 21:00 | Toluca Women v Santos Laguna Women | L | 1-0 |
| Mexico Liga MX Femenil | 2020/11/20 01:00 | Santos Laguna Women v Toluca Women | W | 2-0 |
| Mexico Liga MX Femenil | 2019/11/12 01:00 | Toluca Women v Santos Laguna Women | L | 2-0 |
Home History
| Mexico Liga MX Femenil | 2022/01/22 18:00 | Atlas Women v Santos Laguna Women | L | 1-0 |
| Mexico Liga MX Femenil | 2022/01/20 01:00 | Santos Laguna Women v Club Necaxa Women | D | 1-1 |
| Mexico Liga MX Femenil | 2022/01/11 03:00 | Tijuana Women v Santos Laguna Women | L | 2-1 |
| Mexico Liga MX Femenil | 2021/12/06 18:00 | Atlas Women v Santos Laguna Women | L | 2-1 |
| Mexico Liga MX Femenil | 2021/12/04 00:00 | Santos Laguna Women v Atlas Women | D | 2-2 |
| Mexico Liga MX Femenil | 2021/11/22 03:00 | Santos Laguna Women v Tigres UANL Women | L | 0-2 |
| Mexico Liga MX Femenil | 2021/11/13 23:00 | Queretaro Women v Santos Laguna Women | L | 4-2 |
| Mexico Liga MX Femenil | 2021/11/09 01:00 | Pachuca Women v Santos Laguna Women | L | 4-0 |
Away History
| Mexico Liga MX Femenil | 2022/01/25 03:00 | Chivas Guadalajara Women v Toluca Women | L | 2-0 |
| Mexico Liga MX Femenil | 2022/01/17 23:00 | Toluca Women v Tijuana Women | D | 3-3 |
| Mexico Liga MX Femenil | 2022/01/09 18:00 | Puebla Women v Toluca Women | W | 1-3 |
| Mexico Liga MX Femenil | 2021/11/19 23:00 | Toluca Women v Chivas Guadalajara Women | L | 0-4 |
| Mexico Liga MX Femenil | 2021/11/13 02:00 | Mazatlan FC Women v Toluca Women | W | 0-1 |
| Mexico Liga MX Femenil | 2021/11/08 23:00 | Toluca Women v Leon Women | L | 0-3 |
| Mexico Liga MX Femenil | 2021/10/30 17:00 | Unam Pumas Women v Toluca Women | L | 2-0 |
| Mexico Liga MX Femenil | 2021/10/15 22:00 | Queretaro Women v Toluca Women | W | 0-1 |