Head to Head
| Mexico Liga MX Femenil | 2021/08/24 00:00 | Leon Women v Santos Laguna Women | W | 1-6 |
| Mexico Liga MX Femenil | 2021/02/04 23:00 | Leon Women v Santos Laguna Women | L | 2-1 |
| Mexico Liga MX Femenil | 2020/09/22 00:00 | Santos Laguna Women v Leon Women | D | 1-1 |
| Mexico Liga MX Femenil | 2020/02/25 03:00 | Santos Laguna Women v Leon Women | L | 1-2 |
| Mexico Liga MX Femenil | 2019/09/24 00:00 | Leon Women v Santos Laguna Women | L | 2-0 |
| Mexico Liga MX Femenil | 2019/04/02 03:00 | Leon Women v Santos Laguna Women | L | 1-0 |
| Mexico Liga MX Femenil | 2019/02/05 01:00 | Santos Laguna Women v Leon Women | L | 0-1 |
| Mexico Liga MX Femenil | 2018/10/26 00:00 | Leon Women v Santos Laguna Women | L | 3-0 |
Home History
| Mexico Liga MX Femenil | 2022/02/01 02:00 | Unam Pumas Women v Santos Laguna Women | L | 4-0 |
| Mexico Liga MX Femenil | 2022/01/28 03:00 | Santos Laguna Women v Toluca Women | W | 1-0 |
| Mexico Liga MX Femenil | 2022/01/22 18:00 | Atlas Women v Santos Laguna Women | L | 1-0 |
| Mexico Liga MX Femenil | 2022/01/20 01:00 | Santos Laguna Women v Club Necaxa Women | D | 1-1 |
| Mexico Liga MX Femenil | 2022/01/11 03:00 | Tijuana Women v Santos Laguna Women | L | 2-1 |
| Mexico Liga MX Femenil | 2021/12/06 18:00 | Atlas Women v Santos Laguna Women | L | 2-1 |
| Mexico Liga MX Femenil | 2021/12/04 00:00 | Santos Laguna Women v Atlas Women | D | 2-2 |
| Mexico Liga MX Femenil | 2021/11/22 03:00 | Santos Laguna Women v Tigres UANL Women | L | 0-2 |
Away History
| Mexico Liga MX Femenil | 2022/02/01 01:00 | Leon Women v Queretaro Women | W | 4-2 |
| Mexico Liga MX Femenil | 2022/01/28 01:00 | Leon Women v Tijuana Women | D | 1-1 |
| Mexico Liga MX Femenil | 2022/01/25 01:00 | Pachuca Women v Leon Women | L | 3-0 |
| Mexico Liga MX Femenil | 2022/01/18 03:00 | Leon Women v Juarez FC Women | L | 1-3 |
| Mexico Liga MX Femenil | 2022/01/08 18:00 | Unam Pumas Women v Leon Women | L | 1-0 |
| Mexico Liga MX Femenil | 2021/11/20 16:00 | Club America Women v Leon Women | L | 4-1 |
| Mexico Liga MX Femenil | 2021/11/13 00:00 | Leon Women v Atletico San Luis Women | D | 0-0 |
| Mexico Liga MX Femenil | 2021/11/08 23:00 | Toluca Women v Leon Women | W | 0-3 |