[6] BUF Sabres 4-5 NY Rangers [4] 2022-03-27 21:00
Stadium: Madison Square Garden
Home Manager: Gerard Gallant Away Manager: Don Granato
Head to Head
| NHL | 2021/12/11 00:00 | NY Rangers v BUF Sabres | L | 2-1 |
| NHL | 2021/11/21 23:00 | BUF Sabres v NY Rangers | L | 4-5 |
| NHL | 2021/04/27 23:00 | BUF Sabres v NY Rangers | L | 1-3 |
| NHL | 2021/04/25 22:00 | BUF Sabres v NY Rangers | L | 3-6 |
| NHL | 2021/04/03 23:00 | NY Rangers v BUF Sabres | W | 2-3 |
| NHL | 2021/04/01 23:00 | NY Rangers v BUF Sabres | L | 3-2 |
| NHL | 2021/03/22 23:00 | BUF Sabres v NY Rangers | L | 3-5 |
| NHL | 2021/03/03 00:00 | BUF Sabres v NY Rangers | L | 2-3 |
Home History
| NHL | 2022/03/25 23:00 | WAS Capitals v BUF Sabres | L | 4-3 |
| NHL | 2022/03/23 23:30 | PIT Penguins v BUF Sabres | W | 3-4 |
| NHL | 2022/03/21 02:00 | BUF Sabres v VAN Canucks | W | 3-2 |
| NHL | 2022/03/19 01:00 | BUF Sabres v CAL Flames | W | 1-0 |
| NHL | 2022/03/18 01:00 | BUF Sabres v EDM Oilers | L | 1-6 |
| NHL | 2022/03/13 20:00 | TOR Maple Leafs v BUF Sabres | W | 2-5 |
| NHL | 2022/03/11 00:00 | VGS Golden Knights v BUF Sabres | W | 1-3 |
| NHL | 2022/03/08 00:00 | FLA Panthers v BUF Sabres | L | 6-1 |
Away History
| NHL | 2022/03/25 23:00 | PIT Penguins v NY Rangers | W | 1-5 |
| NHL | 2022/03/22 23:00 | NY Rangers v NJ Devils | L | 4-7 |
| NHL | 2022/03/20 22:00 | NY Rangers v CAR Hurricanes | W | 2-0 |
| NHL | 2022/03/20 00:00 | NY Rangers v TB Lightning | W | 2-1 |
| NHL | 2022/03/17 23:00 | NY Islanders v NY Rangers | L | 2-1 |
| NHL | 2022/03/15 23:00 | ANA Ducks v NY Rangers | W | 3-4 |
| NHL | 2022/03/13 01:00 | NY Rangers v DAL Stars | W | 7-4 |
| NHL | 2022/03/11 01:00 | NY Rangers v STL Blues | L | 2-6 |