Head to Head
| NCAAF | 2015/12/06 01:17 | Iowa v Michigan State | L | 13-16 |
| NCAAF | 2012/10/13 12:00 | Michigan State v Iowa | W | 16-19 |
| NCAAF | 2011/11/12 12:00 | Iowa v Michigan State | L | 21-37 |
| NCAAF | 2010/10/30 12:00 | Iowa v Michigan State | W | 37-6 |
| NCAAF | 2009/10/24 12:00 | Michigan State v Iowa | W | 13-15 |
| NCAAF | 2008/10/04 12:00 | Michigan State v Iowa | L | 16-13 |
| NCAAF | 2007/10/27 12:00 | Iowa v Michigan State | W | 34-27 |
| NCAAF | 2004/10/02 12:00 | Iowa v Michigan State | W | 38-16 |
Home History
| NCAAF | 2017/09/23 23:30 | Penn State v Iowa | L | 21-19 |
| NCAAF | 2017/09/16 19:30 | North Texas v Iowa | W | 14-31 |
| NCAAF | 2017/09/09 16:00 | Iowa v Iowa State | W | 44-41 |
| NCAAF | 2017/09/02 16:00 | Wyoming v Iowa | W | 3-24 |
| NCAAF | 2017/01/02 18:00 | Iowa v Florida | L | 3-30 |
| NCAAF | 2016/11/25 20:30 | Nebraska v Iowa | W | 10-40 |
| NCAAF | 2016/11/19 17:00 | Iowa v Illinois | W | 28-0 |
| NCAAF | 2016/11/13 01:00 | Michigan v Iowa | W | 13-14 |
Away History
| NCAAF | 2017/09/24 00:00 | Notre Dame v Michigan State | L | 38-18 |
| NCAAF | 2017/09/09 19:30 | Western Michigan v Michigan State | W | 14-28 |
| NCAAF | 2017/09/02 16:00 | Bowling Green v Michigan State | W | 10-35 |
| NCAAF | 2016/11/26 20:30 | Michigan State v Penn State | L | 12-45 |
| NCAAF | 2016/11/19 17:00 | Ohio State v Michigan State | L | 17-16 |
| NCAAF | 2016/11/12 17:00 | Rutgers v Michigan State | W | 0-49 |
| NCAAF | 2016/11/05 16:00 | Michigan State v Illinois | L | 27-31 |
| NCAAF | 2016/10/29 16:00 | Michigan v Michigan State | L | 32-23 |