[145] Thanasi Kokkinakis 6-7,7-6,7-6 John Isner [24] 2022-01-12 04:30
Stadium: Centre Court Round: 26 Ground: Hardcourt outdoor
Home History
| ATP Adelaide 2 | 2022/01/11 08:30 | Thanasi Kokkinakis v Benoit Paire | 6-4,6-0 |
| ATP Adelaide | 2022/01/08 10:15 | Gael Monfils v Thanasi Kokkinakis | 7-5,6-0 |
| ATP Adelaide | 2022/01/07 10:45 | Thanasi Kokkinakis v Mikael Ymer | 7-6,4-6,6-4 |
| ATP Adelaide | 2022/01/05 11:05 | Frances Tiafoe v Thanasi Kokkinakis | 6-3,5-7,1-6 |
| ATP Adelaide | 2022/01/04 08:30 | Thanasi Kokkinakis v John Millman | 6-4,6-3 |
| ATP Indian Wells | 2021/10/06 01:00 | Matteo Viola v Thanasi Kokkinakis | 6-3,3-6,7-6 |
| Challenger Sibiu | 2021/10/03 12:00 | Stefano Travaglia v Thanasi Kokkinakis | 7-6,6-2 |
| Challenger Sibiu | 2021/10/02 08:00 | Thanasi Kokkinakis v Marc-Andrea Huesler | 6-2,6-1 |
Away History
| ATP Cup | 2022/01/05 23:00 | Daniel Evans v John Isner | 6-4,7-6 |
| ATP Cup | 2022/01/03 23:00 | Jan-Lennard Struff v John Isner | 7-6,4-6,7-5 |
| ATP Cup | 2022/01/01 23:00 | Brayden Schnur v John Isner | 1-6,3-6 |
| Davis Cup | 2021/11/28 19:10 | John Isner v Daniel Elahi Galan | 3-6,6-3,6-7 |
| Davis Cup | 2021/11/26 16:45 | John Isner v Jannik Sinner | 2-6,0-6 |
| ATP Indian Wells | 2021/10/11 03:30 | John Isner v Yoshihito Nishioka | 6-3,6-4 |
| Laver Cup | 2021/09/25 18:50 | Alexander Zverev v John Isner | 7-6,6-7,10-5 |
| US Open | 2021/08/30 17:35 | John Isner v Brandon Nakashima | 6-7,6-7,3-6 |