[25] Reilly Opelka 7-6,4-6,4-6 Andy Murray [135] 2022-01-14 05:15
Stadium: Ken Rosewall Arena Round: 28 Ground: Hardcourt outdoor
Home History
| ATP Sydney | 2022/01/13 05:30 | Brandon Nakashima v Reilly Opelka | 6-7,2-6 |
| ATP Sydney | 2022/01/12 03:25 | Jordan Thompson v Reilly Opelka | 3-6,2-6 |
| ATP Melbourne | 2022/01/06 09:20 | Maxime Cressy v Reilly Opelka | 4-6,7-6,7-6 |
| Davis Cup | 2021/11/26 15:00 | Reilly Opelka v Lorenzo Sonego | 3-6,6-7 |
| ATP Paris | 2021/11/03 13:35 | Cameron Norrie v Reilly Opelka | 6-3,6-4 |
| ATP Paris | 2021/11/02 11:30 | Filip Krajinovic v Reilly Opelka | 3-6,6-7 |
| ATP Vienna | 2021/10/27 12:00 | Reilly Opelka v Jannik Sinner | 4-6,2-6 |
| ATP Antwerp | 2021/10/19 14:15 | Reilly Opelka v Jenson Brooksby | 4-6,4-6 |
Away History
| ATP Sydney | 2022/01/12 09:50 | Andy Murray v Nikoloz Basilashvili | 6-7,7-6,6-3 |
| ATP Sydney | 2022/01/11 08:00 | Viktor Durasovic v Andy Murray | 3-6,1-6 |
| ATP Melbourne | 2022/01/04 04:25 | Facundo Bagnis v Andy Murray | 6-3,5-7,6-3 |
| Mubadala World Tennis Championship | 2021/12/18 15:00 | Andrey Rublev v Andy Murray | 6-4,7-6 |
| Mubadala World Tennis Championship | 2021/12/17 15:00 | Rafael Nadal v Andy Murray | 3-6,5-7 |
| Mubadala World Tennis Championship | 2021/12/16 14:00 | Daniel Evans v Andy Murray | 3-6,2-6 |
| ATP Stockholm | 2021/11/11 17:00 | Andy Murray v Tommy Paul | 2-6,6-3,3-6 |
| ATP Stockholm | 2021/11/10 17:00 | Jannik Sinner v Andy Murray | 6-7,3-6 |