[70] Maxime Cressy 7-6,7-5,6-7,6-7,6-4 John Isner [25] 2022-01-18 03:15
Stadium: Court 5 Round: 23 Ground: Hardcourt outdoor
Home History
| ATP Sydney | 2022/01/13 09:45 | Daniel Evans v Maxime Cressy | 6-4,7-6 |
| ATP Sydney | 2022/01/13 01:30 | Maxime Cressy v Dusan Lajovic | 6-3,6-4 |
| ATP Sydney | 2022/01/11 07:45 | Maxime Cressy v Adrian Mannarino | 6-3,7-5 |
| ATP Melbourne | 2022/01/09 08:15 | Rafael Nadal v Maxime Cressy | 7-6,6-3 |
| ATP Melbourne | 2022/01/08 04:00 | Grigor Dimitrov v Maxime Cressy | 5-7,6-7 |
| ATP Melbourne | 2022/01/07 06:00 | Jaume Munar v Maxime Cressy | 6-7,4-6 |
| ATP Melbourne | 2022/01/06 09:20 | Maxime Cressy v Reilly Opelka | 4-6,7-6,7-6 |
| ATP Melbourne | 2022/01/05 05:00 | Maxime Cressy v Rinky Hijikata | 6-3,6-0 |
Away History
| ATP Adelaide 2 | 2022/01/12 04:30 | Thanasi Kokkinakis v John Isner | 6-7,7-6,7-6 |
| ATP Cup | 2022/01/05 23:00 | Daniel Evans v John Isner | 6-4,7-6 |
| ATP Cup | 2022/01/03 23:00 | Jan-Lennard Struff v John Isner | 7-6,4-6,7-5 |
| ATP Cup | 2022/01/01 23:00 | Brayden Schnur v John Isner | 1-6,3-6 |
| Davis Cup | 2021/11/28 19:10 | John Isner v Daniel Elahi Galan | 3-6,6-3,6-7 |
| Davis Cup | 2021/11/26 16:45 | John Isner v Jannik Sinner | 2-6,0-6 |
| ATP Indian Wells | 2021/10/11 03:30 | John Isner v Yoshihito Nishioka | 6-3,6-4 |
| Laver Cup | 2021/09/25 18:50 | Alexander Zverev v John Isner | 7-6,6-7,10-5 |