[16] BUF Sabres 1-5 PIT Penguins [6] 2017-12-03 00:00
Stadium: PPG Paints Arena Round: 1
Home Manager: Mike Sullivan Away Manager: Phil Housley
Head to Head
| NHL | 2017/12/02 00:00 | PIT Penguins v BUF Sabres | L | 4-0 |
| NHL | 2017/11/15 00:00 | BUF Sabres v PIT Penguins | L | 4-5 |
| NHL Pre-Season | 2017/09/27 23:00 | BUF Sabres v PIT Penguins | L | 4-5 |
| NHL Pre-Season | 2017/09/19 23:00 | PIT Penguins v BUF Sabres | W | 3-4 |
| NHL | 2017/03/21 23:00 | PIT Penguins v BUF Sabres | L | 3-1 |
| NHL | 2017/03/05 22:00 | BUF Sabres v PIT Penguins | L | 3-4 |
| NHL | 2016/11/20 00:00 | PIT Penguins v BUF Sabres | W | 1-2 |
Home History
| NHL | 2017/12/02 00:00 | PIT Penguins v BUF Sabres | L | 4-0 |
| NHL | 2017/11/29 00:00 | TB Lightning v BUF Sabres | L | 2-0 |
| NHL | 2017/11/26 00:00 | BUF Sabres v MON Canadiens | L | 0-3 |
| NHL | 2017/11/25 00:00 | EDM Oilers v BUF Sabres | W | 1-3 |
| NHL | 2017/11/23 00:00 | MIN Wild v BUF Sabres | L | 5-4 |
| NHL | 2017/11/21 00:00 | CLB Blue Jackets v BUF Sabres | L | 3-2 |
| NHL | 2017/11/19 00:00 | CAR Hurricanes v BUF Sabres | L | 3-1 |
| NHL | 2017/11/18 00:30 | BUF Sabres v DET Red Wings | L | 1-3 |
Away History
| NHL | 2017/12/02 00:00 | PIT Penguins v BUF Sabres | W | 4-0 |
| NHL | 2017/11/28 00:00 | PHI Flyers v PIT Penguins | W | 4-5 |
| NHL | 2017/11/26 00:00 | TB Lightning v PIT Penguins | W | 2-5 |
| NHL | 2017/11/24 18:00 | PIT Penguins v BOS Bruins | L | 3-4 |
| NHL | 2017/11/23 00:00 | VAN Canucks v PIT Penguins | L | 5-2 |
| NHL | 2017/11/19 00:00 | CHI Blackhawks v PIT Penguins | L | 2-1 |
| NHL | 2017/11/17 00:30 | PIT Penguins v OTT Senators | W | 3-1 |
| NHL | 2017/11/15 00:00 | BUF Sabres v PIT Penguins | W | 4-5 |