[7] BUF Sabres 3-7 CLB Blue Jackets [10] 2022-02-20 23:00
Stadium: Nationwide Arena
Home Manager: Brad Larsen Away Manager: Don Granato
Head to Head
| NHL | 2022/02/11 00:00 | CLB Blue Jackets v BUF Sabres | L | 4-3 |
| NHL | 2021/11/23 00:00 | CLB Blue Jackets v BUF Sabres | L | 7-4 |
| NHL Pre-Season | 2021/10/04 23:00 | CLB Blue Jackets v BUF Sabres | L | 5-3 |
| NHL Pre-Season | 2021/09/28 23:00 | BUF Sabres v CLB Blue Jackets | W | 5-4 |
| NHL | 2020/02/14 00:00 | CLB Blue Jackets v BUF Sabres | W | 3-4 |
| NHL | 2020/02/01 18:00 | CLB Blue Jackets v BUF Sabres | W | 1-2 |
| NHL | 2019/10/07 23:00 | BUF Sabres v CLB Blue Jackets | L | 3-4 |
| NHL Pre-Season | 2019/09/25 23:00 | CLB Blue Jackets v BUF Sabres | W | 3-4 |
Home History
| NHL | 2022/02/19 18:00 | COL Avalanche v BUF Sabres | L | 5-3 |
| NHL | 2022/02/18 00:00 | OTT Senators v BUF Sabres | L | 3-1 |
| NHL | 2022/02/16 00:00 | NY Islanders v BUF Sabres | W | 3-6 |
| NHL | 2022/02/13 17:30 | BUF Sabres v MON Canadiens | W | 5-3 |
| NHL | 2022/02/11 00:00 | CLB Blue Jackets v BUF Sabres | L | 4-3 |
| NHL | 2022/02/02 03:00 | BUF Sabres v VGS Golden Knights | L | 2-5 |
| NHL | 2022/01/31 01:00 | BUF Sabres v COL Avalanche | L | 1-4 |
| NHL | 2022/01/30 02:00 | BUF Sabres v ARZ Coyotes | W | 3-1 |
Away History
| NHL | 2022/02/18 01:30 | CLB Blue Jackets v CHI Blackhawks | W | 7-4 |
| NHL | 2022/02/16 02:00 | CLB Blue Jackets v CAL Flames | L | 2-6 |
| NHL | 2022/02/12 17:30 | CLB Blue Jackets v MON Canadiens | W | 2-1 |
| NHL | 2022/02/11 00:00 | CLB Blue Jackets v BUF Sabres | W | 4-3 |
| NHL | 2022/02/09 00:00 | CLB Blue Jackets v WAS Capitals | W | 5-4 |
| NHL | 2022/02/01 00:00 | FLA Panthers v CLB Blue Jackets | L | 8-4 |
| NHL | 2022/01/31 00:00 | CLB Blue Jackets v MON Canadiens | W | 6-3 |
| NHL | 2022/01/28 00:00 | NY Rangers v CLB Blue Jackets | W | 3-5 |